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Ultrasmall Gold Nanorod Vesicles with Enhanced Tumor Accumulation and Fast Excretion from the Body for Cancer Therapy

Song, Jibin ; Yang, Xiangyu ; Jacobson, Orit ; Huang, Peng ; Sun, Xiaolian ; Lin, Lisen ; Yan, Xuefeng ; Niu, Gang ; Ma, Qingjie ; Chen, Xiaoyuan

Advanced materials (Weinheim), 2015-09, Vol.27 (33), p.4910-4917 [Periódico revisado por pares]

Germany: Blackwell Publishing Ltd

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Título:
Ultrasmall Gold Nanorod Vesicles with Enhanced Tumor Accumulation and Fast Excretion from the Body for Cancer Therapy
Autor: Song, Jibin ; Yang, Xiangyu ; Jacobson, Orit ; Huang, Peng ; Sun, Xiaolian ; Lin, Lisen ; Yan, Xuefeng ; Niu, Gang ; Ma, Qingjie ; Chen, Xiaoyuan
Assuntos: Animals ; biodegradation ; Brain Neoplasms - diagnosis ; Brain Neoplasms - metabolism ; Brain Neoplasms - therapy ; Cancer ; Cell Line, Tumor ; Effectiveness ; Excretion ; Gold ; Gold - chemistry ; Gold - metabolism ; Gold - pharmacokinetics ; Humans ; Kinetics ; Lactic Acid - chemistry ; Mice ; Nanostructure ; Nanotubes ; nanovesicles ; photoacoustic imaging ; Photoacoustic Techniques ; photothermal effects ; Polyethylene Glycols - chemistry ; Polyglycolic Acid - chemistry ; Theranostic Nanomedicine ; Therapy ; Tumors ; ultrasmall gold nanorods ; Vesicles
É parte de: Advanced materials (Weinheim), 2015-09, Vol.27 (33), p.4910-4917
Notas: ark:/67375/WNG-GMXG8W87-Q
istex:AF7E8B1C524D2533F5BC608AAD409A6EF0EEC371
ArticleID:ADMA201502486
ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
Descrição: A new kind of ultrasmall dissociable AuNR@PEG/PLGA vesicles (≈60 nm) (AuNR = gold nanorod; PEG = poly(ethylene glycol); PLGA = poly(lactic‐co‐glycolic acid)) assembled from small AuNRs (dimension: ≈8 nm × 2 nm) is reported. They exhibit several striking features: prolonged circulation and prominent tumor accumulation; rapid excretion from the body as AuNR@PEG after therapy; enhanced photoacoustic and photo thermal properties; and high photothermal cancer therapy efficacy.
Editor: Germany: Blackwell Publishing Ltd
Idioma: Inglês

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Ultrasmall Gold Nanorod Vesicles with Enhanced Tumor Accumulation and Fast Excretion from the Body for Cancer Therapy

Song, Jibin ; Yang, Xiangyu ; Jacobson, Orit ; Huang, Peng ; Sun, Xiaolian ; Lin, Lisen ; Yan, Xuefeng ; Niu, Gang ; Ma, Qingjie ; Chen, Xiaoyuan

Germany: Blackwell Publishing Ltd

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