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Stimulation of protein kinase C (PKC) activity in resting swiss 3T3 cells by prostaglandin F sub(2 alpha )

Goin, M ; Jimenez de Asua, L

FEBS letters, 1992-01, Vol.297 (1-2), p.175-178 [Periódico revisado por pares]

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Título:
Stimulation of protein kinase C (PKC) activity in resting swiss 3T3 cells by prostaglandin F sub(2 alpha )
Autor: Goin, M ; Jimenez de Asua, L
Assuntos: 3T3 cells ; activity ; prostaglandin F2 alpha ; protein kinase C ; stimulation
É parte de: FEBS letters, 1992-01, Vol.297 (1-2), p.175-178
Notas: ObjectType-Article-1
SourceType-Scholarly Journals-1
content type line 23
ObjectType-Feature-2
Descrição: Prostaglandin F sub(2 alpha ) (PGF sub(2 alpha )), a mitogen for resting Swiss 3T3 cells, rapidly stimulates phosphorylation of an 80 kDa protein (80 K). 1-Oleoyl-2-acetylglycerol (OAG) and 12-O-tetradecanoyl phorbol-13-acetate (TPA) both protein kinase C (PKC) activators, also elicit 80 K phosphorylation. The results suggest that PGF sub(2 alpha ) mitogenic induction involves PKC signalling pathway activation while its enhancement by PGE sub(1) or PGE sub(2) occurs through a different mechanism(s).
Idioma: Inglês

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