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Appetite-Suppressing and Satiety-Increasing Bioactive Phytochemicals: A Systematic Review

Stuby, Johann ; Gravestock, Isaac ; Wolfram, Evelyn ; Pichierri, Giuseppe ; Steurer, Johann ; Burgstaller, Jakob M

Nutrients, 2019-09, Vol.11 (9), p.2238 [Periódico revisado por pares]

Switzerland: MDPI AG

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Título:
Appetite-Suppressing and Satiety-Increasing Bioactive Phytochemicals: A Systematic Review
Autor: Stuby, Johann ; Gravestock, Isaac ; Wolfram, Evelyn ; Pichierri, Giuseppe ; Steurer, Johann ; Burgstaller, Jakob M
Assuntos: Appetite ; Appetite Depressants - adverse effects ; Appetite Depressants - therapeutic use ; Appetite Regulation - drug effects ; bioactive phytochemicals ; Biological activity ; Body mass index ; Body weight loss ; Comparative analysis ; Dietary supplements ; Drug therapy ; Emptying ; Energy ; Feeding Behavior - drug effects ; Female ; Food ; fullness ; Gastric emptying ; Gastrointestinal surgery ; Glucose ; Green tea ; Heterogeneity ; Humans ; hunger ; Male ; Metabolism ; Metabolites ; Obesity ; Obesity - drug therapy ; Obesity - epidemiology ; Obesity - physiopathology ; Obesity - psychology ; Patients ; Peptides ; Pharmaceuticals ; Pharmacovigilance ; Phytochemicals ; Phytochemicals - adverse effects ; Phytochemicals - therapeutic use ; plant extracts ; Plants (botany) ; Prescription drugs ; Product safety ; Randomized Controlled Trials as Topic ; Regulation ; Review ; Satiety ; Satiety Response - drug effects ; Statistical analysis ; Systematic review ; Tea ; Treatment Outcome ; Weight control ; Weight loss ; Weight Loss - drug effects
É parte de: Nutrients, 2019-09, Vol.11 (9), p.2238
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Stuby and Gravestock contributed equally to this work.
Descrição: The prevalence of obesity is increasing worldwide. Bioactive phytochemicals in food supplements are a trending approach to facilitate dieting and to improve patients' adherence to reducing food and caloric intake. The aim of this systematic review was to assess efficacy and safety of the most commonly used bioactive phytochemicals with appetite/hunger-suppressing and/or satiety/fullness-increasing properties. To be eligible, studies needed to have included at least 10 patients per group aged 18 years or older with no serious health problems except for overweight or obesity. Of those studies, 32 met the inclusion criteria, in which 27 different plants were tested alone or as a combination, regarding their efficacy in suppressing appetite/hunger and/or increasing satiety/fullness. The plant extracts most tested were derived from (green tea), , and species. None of the plant extracts tested in several trials showed a consistent positive treatment effect. Furthermore, only a few adverse events were reported, but none serious. The findings revealed mostly inconclusive evidence that the tested bioactive phytochemicals are effective in suppressing appetite/hunger and/or increasing satiety/fullness. More systematic and high quality clinical studies are necessary to determine the benefits and safety of phytochemical complementary remedies for dampening the feeling of hunger during dieting.
Editor: Switzerland: MDPI AG
Idioma: Inglês

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Appetite-Suppressing and Satiety-Increasing Bioactive Phytochemicals: A Systematic Review

Stuby, Johann ; Gravestock, Isaac ; Wolfram, Evelyn ; Pichierri, Giuseppe ; Steurer, Johann ; Burgstaller, Jakob M

Switzerland: MDPI AG

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