skip to main content
Idioma:

The Relationship between Metabolic Syndrome and Osteoporosis: A Review

Wong, Sok Kuan ; Chin, Kok-Yong ; Suhaimi, Farihah Hj ; Ahmad, Fairus ; Ima-Nirwana, Soelaiman

Nutrients, 2016-06, Vol.8 (6), p.347 [Periódico revisado por pares]

Switzerland: MDPI AG

Texto completo disponível

Citações Citado por
  • Título:
    The Relationship between Metabolic Syndrome and Osteoporosis: A Review
  • Autor: Wong, Sok Kuan ; Chin, Kok-Yong ; Suhaimi, Farihah Hj ; Ahmad, Fairus ; Ima-Nirwana, Soelaiman
  • Assuntos: Animals ; bone ; Bone and Bones - metabolism ; Bone Density ; dyslipidaemia ; Gene Expression Regulation - physiology ; Humans ; hyperglycaemia ; hypertension ; Metabolic Syndrome - complications ; obesity ; osteoporosis ; Osteoporosis - etiology ; Review
  • É parte de: Nutrients, 2016-06, Vol.8 (6), p.347
  • Notas: ObjectType-Article-2
    SourceType-Scholarly Journals-1
    ObjectType-Feature-3
    content type line 23
    ObjectType-Review-1
  • Descrição: Metabolic syndrome (MetS) and osteoporosis are two major healthcare problems worldwide. Metabolic syndrome is a constellation of medical conditions consisting of central obesity, hyperglycemia, hypertension, and dyslipidemia, in which each acts on bone tissue in different ways. The growing prevalence of MetS and osteoporosis in the population along with the controversial findings on the relationship between both conditions suggest the importance for further investigation and discussion on this topic. This review aims to assess the available evidence on the effects of each component of MetS on bone metabolism from the conventional to the contemporary. Previous studies suggested that the two conditions shared some common underlying pathways, which include regulation of calcium homeostasis, receptor activator of NF-κB ligand (RANKL)/receptor activator of the NF-κB (RANK)/osteoprotegerin (OPG) and Wnt-β-catenin signaling pathways. In conclusion, we suggest that MetS may have a potential role in developing osteoporosis and more studies are necessary to further prove this hypothesis.
  • Editor: Switzerland: MDPI AG
  • Idioma: Inglês
Links
Voltar para lista de resultados

  • Realização: ABCD-USP USP   Logos de Redes Sociais: Freepik

Buscando em bases de dados remotas. Favor aguardar.