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Female genital tuberculosis: Revisited

Sharma, Jai ; Sharma, Eshani ; Sharma, Sangeeta ; Dharmendra, Sona

Indian journal of medical research (New Delhi, India : 1994), 2018-12, Vol.148 (7), p.71-83 [Revista revisada por pares]

India: Wolters Kluwer India Pvt. Ltd

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Título:
Female genital tuberculosis: Revisited
Autor: Sharma, Jai ; Sharma, Eshani ; Sharma, Sangeeta ; Dharmendra, Sona
Materias: Abdomen ; Biopsy ; Cancer therapies ; Care and treatment ; Causes of ; Complications and side effects ; Cysts ; Developing countries ; Diagnosis ; Disease ; Drugs ; Endoscopy ; Ethambutol - therapeutic use ; Fallopian tubes - female genital tuberculosis - GeneXpert - infertility - Mycobacterium tuberculosis ; Fallopian Tubes - microbiology ; Fallopian Tubes - pathology ; Female ; Female genital diseases ; HIV ; Human immunodeficiency virus ; Humans ; Infections ; Infertility ; Isoniazid - therapeutic use ; Laparoscopy ; LDCs ; Menstruation ; Methylene blue ; Morbidity ; Mortality ; Mycobacterium tuberculosis - drug effects ; Mycobacterium tuberculosis - pathogenicity ; Ovarian cancer ; Pregnancy ; Review ; Rifampin - therapeutic use ; Substance abuse treatment ; Surrogate mothers ; Tuberculosis ; Tuberculosis, Female Genital - diagnosis ; Tuberculosis, Female Genital - drug therapy ; Tuberculosis, Female Genital - microbiology ; Tuberculosis, Female Genital - pathology ; Ulcers ; Womens health
Es parte de: Indian journal of medical research (New Delhi, India : 1994), 2018-12, Vol.148 (7), p.71-83
Notas: ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
Descripción: Female genital tuberculosis (FGTB) is caused by Mycobacterium tuberculosis (rarely Mycobacterium bovis and/or atypical mycobacteria) being usually secondary to TB of the lungs or other organs with infection reaching through haematogenous, lymphatic route or direct spread from abdominal TB. In FGTB, fallopian tubes are affected in 90 per cent women, whereas uterine endometrium is affected in 70 per cent and ovaries in about 25 per cent women. It causes menstrual dysfunction and infertility through the damage of genital organs. Some cases may be asymptomatic. Diagnosis is often made from proper history taking, meticulous clinical examination and judicious use of investigations, especially endometrial aspirate (or biopsy) and endoscopy. Treatment is through multi-drug antitubercular treatment for adequate time period (rifampicin, isoniazid, pyrazinamide, ethambutol daily for 60 days followed by rifampicin, isoniazid, ethambutol daily for 120 days). Treatment is given for 18-24 months using the second-line drugs for drug-resistant (DR) cases. With the advent of increased access to rapid diagnostics and newer drugs, the management protocol is moving towards achieving universal drug sensitivity testing and treatment with injection-free regimens containing newer drugs, especially for new and previously treated DR cases.
Editor: India: Wolters Kluwer India Pvt. Ltd
Idioma: Inglés

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Female genital tuberculosis: Revisited

Sharma, Jai ; Sharma, Eshani ; Sharma, Sangeeta ; Dharmendra, Sona

India: Wolters Kluwer India Pvt. Ltd

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