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Depression in adolescence

Thapar, Anita, Prof ; Collishaw, Stephan, DPhil ; Pine, Daniel S, MD ; Thapar, Ajay K, PhD

The Lancet (British edition), 2012-03, Vol.379 (9820), p.1056-1067 [Periódico revisado por pares]

Kidlington: Elsevier Ltd

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Título:
Depression in adolescence
Autor: Thapar, Anita, Prof ; Collishaw, Stephan, DPhil ; Pine, Daniel S, MD ; Thapar, Ajay K, PhD
Assuntos: Adolescent ; Adolescents ; Adult and adolescent clinical studies ; Biological and medical sciences ; Children & youth ; Depression ; Depressive Disorder - diagnosis ; Depressive Disorder - epidemiology ; Depressive Disorder - genetics ; Depressive Disorder - therapy ; Diagnosis, Differential ; Female ; General aspects ; Genetics ; Hormones ; Humans ; Incidence ; Internal Medicine ; Male ; Medical sciences ; Mental depression ; Miscellaneous ; Mood disorders ; Morbidity ; Prevalence ; prevention ; Psychology. Psychoanalysis. Psychiatry ; Psychopathology. Psychiatry ; Risk Factors ; Stress ; Studies ; suicide ; Teenagers ; United Kingdom - epidemiology ; United States - epidemiology ; Young Adult
É parte de: The Lancet (British edition), 2012-03, Vol.379 (9820), p.1056-1067
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Descrição: Summary Unipolar depressive disorder in adolescence is common worldwide but often unrecognised. The incidence, notably in girls, rises sharply after puberty and, by the end of adolescence, the 1 year prevalence rate exceeds 4%. The burden is highest in low-income and middle-income countries. Depression is associated with substantial present and future morbidity, and heightens suicide risk. The strongest risk factors for depression in adolescents are a family history of depression and exposure to psychosocial stress. Inherited risks, developmental factors, sex hormones, and psychosocial adversity interact to increase risk through hormonal factors and associated perturbed neural pathways. Although many similarities between depression in adolescence and depression in adulthood exist, in adolescents the use of antidepressants is of concern and opinions about clinical management are divided. Effective treatments are available, but choices are dependent on depression severity and available resources. Prevention strategies targeted at high-risk groups are promising.
Editor: Kidlington: Elsevier Ltd
Idioma: Inglês

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Depression in adolescence

Thapar, Anita, Prof ; Collishaw, Stephan, DPhil ; Pine, Daniel S, MD ; Thapar, Ajay K, PhD

Kidlington: Elsevier Ltd

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