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Candida spp. with acquired echinocandin resistance, France, 2004-2010

Dannaoui, Eric ; Desnos-Ollivier, Marie ; Garcia-Hermoso, Dea ; Grenouillet, Fredéric ; Cassaing, Sophie ; Baixench, Marie-Thérèse ; Bretagne, Stéphane ; Dromer, Françoise ; Lortholary, Olivier

Emerging infectious diseases, 2012-01, Vol.18 (1), p.86-90 [Periódico revisado por pares]

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Título:
Candida spp. with acquired echinocandin resistance, France, 2004-2010
Autor: Dannaoui, Eric ; Desnos-Ollivier, Marie ; Garcia-Hermoso, Dea ; Grenouillet, Fredéric ; Cassaing, Sophie ; Baixench, Marie-Thérèse ; Bretagne, Stéphane ; Dromer, Françoise ; Lortholary, Olivier
Assuntos: Adolescent ; Adult ; Aged ; Aged, 80 and over ; Antifungal Agents ; Antifungal Agents - pharmacology ; Candida ; Candida - classification ; Candida - drug effects ; Candida albicans ; Candida glabrata ; Candida krusei ; Candidiasis ; Candidiasis - epidemiology ; Candidiasis - microbiology ; caspofungin ; Drug Resistance, Fungal ; Echinocandins ; Echinocandins - pharmacology ; Female ; FKS mutation ; France ; France - epidemiology ; Humans ; Life Sciences ; Male ; Microbial Sensitivity Tests ; Microbiology and Parasitology ; Middle Aged ; Mycology ; Young Adult
É parte de: Emerging infectious diseases, 2012-01, Vol.18 (1), p.86-90
Notas: ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
PMCID: PMC3310099
Descrição: We report 20 episodes of infection caused by acquired echinocandin-resistant Candida spp. harboring diverse and new Fksp mutations. For 12 patients, initial isolates (low MIC, wild-type Fksp sequence) and subsequent isolates (after caspofungin treatment, high MIC, mutated Fksp) were genetically related.
Editor: United States: Centers for Disease Control and Prevention
Idioma: Inglês

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