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Reducing the risk of blood-transmitted infections of HIV, hepatitis B or C virus in a teaching hospital in Amsterdam--evaluation of a protocol for needlestick accidents among hospital staff during the period 1997-2001

Regez, R M ; Rietra, P J G M ; van der Linden, C Th M ; Frissen, P H J ; Weigel, H M ; Brinkman, K

Nederlands tijdschrift voor geneeskunde, 2002-03, Vol.146 (13), p.617

Netherlands

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  • Título:
    Reducing the risk of blood-transmitted infections of HIV, hepatitis B or C virus in a teaching hospital in Amsterdam--evaluation of a protocol for needlestick accidents among hospital staff during the period 1997-2001
  • Autor: Regez, R M ; Rietra, P J G M ; van der Linden, C Th M ; Frissen, P H J ; Weigel, H M ; Brinkman, K
  • Materias: Adult ; Cross Infection - prevention & control ; Female ; Follow-Up Studies ; Hepatitis B - transmission ; Hepatitis C - transmission ; HIV Infections - transmission ; Humans ; Infectious Disease Transmission, Patient-to-Professional - prevention & control ; Male ; Needlestick Injuries ; Netherlands ; Occupational Exposure ; Personnel, Hospital ; Prospective Studies ; Seroepidemiologic Studies
  • Es parte de: Nederlands tijdschrift voor geneeskunde, 2002-03, Vol.146 (13), p.617
  • Descripción: To evaluate a protocol for hospital staff aimed at reducing their risk of exposure to blood-transmitted infections. Prospective. In August 1997 a protocol was introduced to the Onze Lieve Vrouwe Gasthuis Hospital in Amsterdam, with procedures to be followed after percutaneous or mucocutaneous blood contact in which there was a chance of transmission of hepatitis B (HBV) or C (HCV), as well as guidelines for the prescription of post-exposure prophylaxis (PEP) after accidents with an HIV risk. In the period 1 August 1997-30 June 2001 data were collected from registration forms that reported accidents and the ensuing events. A total of 403 accidents were reported by 138 (34.2%) physicians, 135 (33.5%) ward nurses, 46 (11.4%) operation assistants, 30 (7.4%) co-assistants, 21 (5.2%) analysts and 33 (8.2%) persons with another position. There was a constant increase in the number of reports over the period. The seroprevalence of the source patients was: 6.9% (25/360) HIV, 8.1% (6/74) HBV and 6.3% (23/363) HCV. PEP was prescribed on 46 occasions: 15 times for an HIV positive source and 31 times for what was initially an unknown HIV source. Following the introduction of a rapid HIV test in September 1999, there was a reduction in the number of unnecessary PEP prescriptions from 4 in 1997, 7 in 1998 and 16 in 1999 to 3 in 2000 and 1 in 2001. All 15 persons who were correctly started on a PEP treatment took the medication for a period of 28 days despite many side effects. No seroconversions were established during the follow-up period of 6 months.
  • Editor: Netherlands
  • Idioma: Holandés

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