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The difference between fingerstick and venous hemoglobin and hematocrit varies by sex and iron stores

Cable, Ritchard G. ; Steele, Whitney R. ; Melmed, Russell S. ; Johnson, Bryce ; Mast, Alan E. ; Carey, Patricia M. ; Kiss, Joseph E. ; Kleinman, Steven H. ; Wright, David J.

Transfusion (Philadelphia, Pa.), 2012-05, Vol.52 (5), p.1031-1040 [Periódico revisado por pares]

Malden, USA: Blackwell Publishing Inc

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Título:
The difference between fingerstick and venous hemoglobin and hematocrit varies by sex and iron stores
Autor: Cable, Ritchard G. ; Steele, Whitney R. ; Melmed, Russell S. ; Johnson, Bryce ; Mast, Alan E. ; Carey, Patricia M. ; Kiss, Joseph E. ; Kleinman, Steven H. ; Wright, David J.
Assuntos: Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy ; Biological and medical sciences ; Blood and lymphatic vessels ; Blood Donors ; Blood Specimen Collection - methods ; Blood. Blood and plasma substitutes. Blood products. Blood cells. Blood typing. Plasmapheresis. Apheresis ; Cardiology. Vascular system ; Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous ; Female ; Hematocrit ; Hemoglobins - analysis ; Humans ; Iron - metabolism ; Linear Models ; Male ; Medical sciences ; Sex Factors ; Transfusions. Complications. Transfusion reactions. Cell and gene therapy
É parte de: Transfusion (Philadelphia, Pa.), 2012-05, Vol.52 (5), p.1031-1040
Notas: ark:/67375/WNG-92T4RMPT-B
istex:FC71AB48E42D11F3FCC4AB809F3AFBDDF6A0BE3E
ArticleID:TRF3389
This work was supported by NHLBI Contracts N01‐HB‐47168, ‐47169, ‐47171, ‐47172, and ‐47175.
ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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Descrição: BACKGROUND: Fingerstick blood samples are used to estimate donor venous hemoglobin (Hb). STUDY DESIGN AND METHODS: Fingerstick Hb or hematocrit (Hct) was determined routinely for 2425 selected donors at six blood centers, along with venous Hb. Using sex and measures of iron status including absent iron stores (AIS; ferritin < 12 ng/mL), linear regression models were developed to predict venous Hb from fingerstick. RESULTS: Across all subjects, fingerstick Hb was higher than venous Hb in the higher part of the clinical range, but lower in the lower part of the range. The relationship varied by sex and iron status. Across centers, a female donor had on average a venous Hb result 0.5 to 0.8 g/dL lower than a male donor with the same fingerstick Hb and iron status. Similarly, a donor with AIS had on average a venous Hb result 0.3 to 1.1 g/dL lower than an iron‐replete donor with the same fingerstick value and sex. An iron‐replete male donor with a fingerstick result at the cutoff (Hb 12.5 g/dL) had an acceptable expected venous Hb (12.8 to 13.8 g/dL). A female donor with AIS with a fingerstick result at the cutoff had an expected venous Hb below 12.5 g/dL (11.7 to 12.4 g/dL). Of females with AIS, 40.2% donated blood when their venous Hb was less than 12.5 g/dL. CONCLUSIONS: Fingerstick is considered a useful estimator of venous Hb. However, in some donor groups, particularly female donors with AIS, fingerstick overestimates venous Hb at the donation cutoff. This significant limitation should be considered in setting donor fingerstick Hb or Hct requirements.
Editor: Malden, USA: Blackwell Publishing Inc
Idioma: Inglês

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The difference between fingerstick and venous hemoglobin and hematocrit varies by sex and iron stores

Cable, Ritchard G. ; Steele, Whitney R. ; Melmed, Russell S. ; Johnson, Bryce ; Mast, Alan E. ; Carey, Patricia M. ; Kiss, Joseph E. ; Kleinman, Steven H. ; Wright, David J.

Malden, USA: Blackwell Publishing Inc

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