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Herpesvirus: an underestimated virus

Rechenchoski, Daniele Zendrini ; Faccin-Galhardi, Ligia Carla ; Linhares, Rosa Elisa Carvalho ; Nozawa, Carlos

Folia microbiologica, 2017-03, Vol.62 (2), p.151-156 [Periódico revisado por pares]

Dordrecht: Springer Netherlands

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Título:
Herpesvirus: an underestimated virus
Autor: Rechenchoski, Daniele Zendrini ; Faccin-Galhardi, Ligia Carla ; Linhares, Rosa Elisa Carvalho ; Nozawa, Carlos
Assuntos: Antiviral Agents - therapeutic use ; Applied Microbiology ; Biomedical and Life Sciences ; Cytomegalovirus ; Disease ; Drug resistance ; Environmental Engineering/Biotechnology ; Epidemiology ; Genes ; Genomes ; Glycoproteins ; Health services ; Heparan sulfate ; Herpes Genitalis - diagnosis ; Herpes Genitalis - drug therapy ; Herpes Genitalis - epidemiology ; Herpes Genitalis - immunology ; Herpes simplex ; Herpes Simplex - diagnosis ; Herpes Simplex - drug therapy ; Herpes Simplex - epidemiology ; Herpes Simplex - immunology ; Herpes viruses ; Herpesviridae ; Herpesvirus 1, Human - classification ; Herpesvirus 1, Human - drug effects ; Herpesvirus 1, Human - growth & development ; Herpesvirus 1, Human - pathogenicity ; Herpesvirus 2, Human - classification ; Herpesvirus 2, Human - drug effects ; Herpesvirus 2, Human - growth & development ; Herpesvirus 2, Human - pathogenicity ; Humans ; Immunocompromised Host ; Immunology ; Infant, Newborn ; Infections ; Life Sciences ; Microbiology ; Mortality ; Neonates ; Palliative care ; Pathogenesis ; Prophylaxis ; Proteins ; RNA polymerase ; Taxonomy ; Toxicity ; Vaccines ; Virus Replication - drug effects ; Virus Replication - genetics ; Viruses
É parte de: Folia microbiologica, 2017-03, Vol.62 (2), p.151-156
Notas: ObjectType-Article-2
SourceType-Scholarly Journals-1
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ObjectType-Review-1
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Descrição: Herpes simplex virus (HSV) infections are common and widespread; nevertheless, their outcome can be of unpredictable prognosis in neonates and in immunosuppressed patients. Anti-HSV therapy is effective, but the emergence of drug-resistant strains or the drug toxicity that hamper the treatment is of great concern. Vaccine has not yet shown relevant benefit; therefore, palliative prophylactic measures have been adopted to prevent diseases. This short review proposes to present concisely the history of HSV, its taxonomy, physical structure, and replication and to explore the pathogenesis of the infection, clinical manifestations, laboratory diagnosis, treatment, prophylaxis and epidemiology of the diseases.
Editor: Dordrecht: Springer Netherlands
Idioma: Inglês

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Herpesvirus: an underestimated virus

Rechenchoski, Daniele Zendrini ; Faccin-Galhardi, Ligia Carla ; Linhares, Rosa Elisa Carvalho ; Nozawa, Carlos

Dordrecht: Springer Netherlands

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