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Histocompatibility Antigens on Murine Tumors

Goodenow, Robert S. ; Vogel, Julie M. ; Linsk, Richard L.

Science (American Association for the Advancement of Science), 1985-11, Vol.230 (4727), p.777-783 [Periódico revisado por pares]

Washington, DC: The American Association for the Advancement of Science

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Título:
Histocompatibility Antigens on Murine Tumors
Autor: Goodenow, Robert S. ; Vogel, Julie M. ; Linsk, Richard L.
Assuntos: AKR murine leukemia virus ; Animals ; Antigens ; Biological and medical sciences ; Cancer ; Cancer research ; Cellular immunity ; Cricetinae ; DNA, Neoplasm - genetics ; Genetic research ; H-2 Antigens - immunology ; Histocompatibility Antigens - genetics ; Histocompatibility antigens class I ; HLA antigens ; HLA histocompatibility antigens ; Host-tumor relations. Immunology. Biological markers ; Humans ; Immune response ; Immunologic research ; Immunological research ; Leukemia Virus, Murine - genetics ; Leukemia, Experimental - genetics ; Leukemia, Experimental - immunology ; Major Histocompatibility Complex ; Medical sciences ; MHC class I genes ; Mice ; Mice, Inbred BALB C ; Mice, Inbred C57BL ; Molecules ; Natural killer cells ; Neoplasm Transplantation ; Neoplasms - genetics ; Neoplasms - immunology ; Neoplasms, Experimental - genetics ; Neoplasms, Experimental - immunology ; Neoplasms, Radiation-Induced - genetics ; Neoplasms, Radiation-Induced - immunology ; Physiological aspects ; Rats ; Retroviridae - genetics ; T lymphocytes ; T-Lymphocytes, Cytotoxic - immunology ; Tumors
É parte de: Science (American Association for the Advancement of Science), 1985-11, Vol.230 (4727), p.777-783
Descrição: Recent advances in tumor immunology suggest that the expression of the histocompatibility antigens, encoded by the major histocompatibility complex, is important in controlling the metastatic growth of certain murine tumors. The anomalous expression of histocompatibility antigens in many neoplasms appears to be associated with the ability of these cells to evade the immune system and progress to metastasis. This review examines some of the underlying molecular and immunobiological interactions that might determine the metastatic outcome of cellular transformation.
Editor: Washington, DC: The American Association for the Advancement of Science
Idioma: Inglês

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Histocompatibility Antigens on Murine Tumors

Goodenow, Robert S. ; Vogel, Julie M. ; Linsk, Richard L.

Washington, DC: The American Association for the Advancement of Science

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