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Automatically Determining the Confocal Parameters From OCT B-Scans for Quantification of the Attenuation Coefficients

Dwork, Nicholas ; Smith, Gennifer T. ; Leng, Theodore ; Pauly, John M. ; Bowden, Audrey K.

IEEE transactions on medical imaging, 2019-01, Vol.38 (1), p.261-268

United States: IEEE

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Título:
Automatically Determining the Confocal Parameters From OCT B-Scans for Quantification of the Attenuation Coefficients
Autor: Dwork, Nicholas ; Smith, Gennifer T. ; Leng, Theodore ; Pauly, John M. ; Bowden, Audrey K.
Assuntos: Algorithms ; Animals ; Approximation algorithms ; Attenuation ; attenuation coefficient ; Attenuation coefficients ; Bioindicators ; Biomarkers ; Biomedical image processing ; confocal function ; Diagnostic software ; Diagnostic systems ; Eye - diagnostic imaging ; Focal plane ; Humans ; Image Processing, Computer-Assisted - methods ; Imagery ; Imaging ; Optical Coherence Tomography ; optimization ; Parameter estimation ; Phantoms, Imaging ; Rabbits ; Retina - diagnostic imaging ; Scattering ; Signal to noise ratio ; Tomography, Optical Coherence - methods ; Zirconium
É parte de: IEEE transactions on medical imaging, 2019-01, Vol.38 (1), p.261-268
Notas: ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
Descrição: The attenuation coefficient is a relevant biomarker for many diagnostic medical applications. Recently, the Depth-Resolved Confocal (DRC) technique was developed to automatically estimate the attenuation coefficients from Optical Coherence Tomography (OCT) data with pixel-level resolution. However, DRC requires that the confocal function parameters (i.e., focal plane location and apparent Rayleigh range) be known a priori. In this paper, we present the autoConfocal algorithm: a simple, automatic method for estimating those parameters directly from OCT imagery when the focal plane is within the sample. We present autoConfocal+DRC results on phantom data, ex-vivo biological tissue data, and in-vivo clinical data.
Editor: United States: IEEE
Idioma: Inglês

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Automatically Determining the Confocal Parameters From OCT B-Scans for Quantification of the Attenuation Coefficients

Dwork, Nicholas ; Smith, Gennifer T. ; Leng, Theodore ; Pauly, John M. ; Bowden, Audrey K.

United States: IEEE

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