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Changes of mouse cytokines and Th1/Th2 balance in acute stress induced by millimeter-wave

SUN, Rong ; MA, Qiong ; DU, Li ; Jin-ling, CAI ; Xiao-yun, YANG ; GAO, Yan ; Yu-fang, CUI ; MAO, Jian-ping

Jie fang jun yi xue za zhi, 2013-01, Vol.38 (10), p.859 [Periódico revisado por pares]

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Título:
Changes of mouse cytokines and Th1/Th2 balance in acute stress induced by millimeter-wave
Autor: SUN, Rong ; MA, Qiong ; DU, Li ; Jin-ling, CAI ; Xiao-yun, YANG ; GAO, Yan ; Yu-fang, CUI ; MAO, Jian-ping
Assuntos: Cytokines
É parte de: Jie fang jun yi xue za zhi, 2013-01, Vol.38 (10), p.859
Descrição: Objective　To explore the regular pattern of variation of cytokines, especially the Th1/Th2 cytokines, and its effect on immune balance in stress induced by 35GHz millimeter-wave (MMW) exposure in mice. Methods　BALB/c mice were exposed to 420mW/cm2, 35GHz MMW for 60s, and the dorsal skin temperature was real-time monitored with infrared monitor during the period of exposure. Peripheral WBC, thymic and splenic indexes of mice were detected at different time points after MMW exposure. Meanwhile, the contents of serum IL-1β, IL-2, IL-6 and Th1/Th2 cytokines IFN-γ, IL-4 were analyzed by ELISA. Results　The temperature of ear auricle rapidly increased to 50℃ after initiation of exposure, and continuously rose to about 60℃ at 50s to 60s. Peripheral WBC and lymphocytes showed transient reduction at 6h and restored to the control level from 1 to 7d after radiation exposure. Compared with control group, thymus index displayed a transient increase at 6h and thereafter decreased, and then diminished to which significantly
Editor: Beijing: People's Military Medical Press
Idioma: Chinês

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