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Sustained benefit at 2 years of primary femoropopliteal stenting compared with balloon angioplasty with optional stenting

SCHILLINGER, Martin ; SABETI, Schila ; DICK, Petra ; AMIGHI, Jasmin ; MLEKUSCH, Wolfgang ; SCHLAGER, Oliver ; LOEWE, Christian ; CEJNA, Manfred ; LAMMER, Johannes ; MINAR, Erich

Circulation (New York, N.Y.), 2007-05, Vol.115 (21), p.2745-2749 [Periódico revisado por pares]

Hagerstown, MD: Lippincott Williams & Wilkins

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Título:
Sustained benefit at 2 years of primary femoropopliteal stenting compared with balloon angioplasty with optional stenting
Autor: SCHILLINGER, Martin ; SABETI, Schila ; DICK, Petra ; AMIGHI, Jasmin ; MLEKUSCH, Wolfgang ; SCHLAGER, Oliver ; LOEWE, Christian ; CEJNA, Manfred ; LAMMER, Johannes ; MINAR, Erich
Assuntos: Aged ; Alloys ; Angioplasty, Balloon - standards ; Arterial Occlusive Diseases - therapy ; Biological and medical sciences ; Blood and lymphatic vessels ; Cardiology. Vascular system ; Diseases of the cardiovascular system ; Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous ; Exercise Test ; Female ; Femoral Artery ; Follow-Up Studies ; Graft Occlusion, Vascular - diagnostic imaging ; Humans ; Male ; Medical sciences ; Middle Aged ; Peripheral Vascular Diseases - therapy ; Popliteal Artery ; Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects) ; Stents - standards ; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases ; Surgery of the heart ; Treatment Outcome ; Ultrasonography
É parte de: Circulation (New York, N.Y.), 2007-05, Vol.115 (21), p.2745-2749
Notas: ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-News-1
ObjectType-Feature-3
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Descrição: Primary stenting with self-expanding nitinol stents of the superficial femoral artery yielded improved morphological and clinical results compared with balloon angioplasty with optional stenting until 12 months in a randomized controlled trial. We now report 2-year data on restenosis and clinical outcomes of these patients. Of 104 patients with chronic limb ischemia and superficial femoral artery obstructions, 98 (94%) could be followed up until 2 years after intervention for occurrence of restenosis (>50%) by duplex ultrasound and for clinical and hemodynamic outcome by treadmill walking distance and ankle brachial index. Restenosis rates at 2 years were 45.7% (21 of 46) versus 69.2% (36 of 52) in favor of primary stenting compared with balloon angioplasty with optional secondary stenting by an intention-to-treat analysis (P=0.031). Consistently, stenting (whether primary or secondary; n=63) was superior to plain balloon angioplasty (n=35) with respect to the occurrence of restenosis (49.2% versus 74.3%; P=0.028) by a treatment-received analysis. Clinically, patients in the primary stent group showed a trend toward better treadmill walking capacity (average, 302 versus 196 m; P=0.12) and better ankle brachial index values (average, 0.88 versus 0.78; P=0.09) at 2 years, respectively. Reintervention rates tended to be lower after primary stenting (17 of 46 [37.0%] versus 28 of 52 [53.8%]; P=0.14). At 2 years, primary stenting with self-expanding nitinol stents for the treatment of superficial femoral artery obstructions yields a sustained morphological benefit and a trend toward clinical benefit compared with balloon angioplasty with optional stenting.
Editor: Hagerstown, MD: Lippincott Williams & Wilkins
Idioma: Inglês

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Sustained benefit at 2 years of primary femoropopliteal stenting compared with balloon angioplasty with optional stenting

SCHILLINGER, Martin ; SABETI, Schila ; DICK, Petra ; AMIGHI, Jasmin ; MLEKUSCH, Wolfgang ; SCHLAGER, Oliver ; LOEWE, Christian ; CEJNA, Manfred ; LAMMER, Johannes ; MINAR, Erich

Hagerstown, MD: Lippincott Williams & Wilkins

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