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Application of Array-Based Oligonucleotides for Synthesis of Genetic Designs

Sinyakov, A. N. ; Ryabinin, V. A. ; Kostina, E. V.

Molecular biology (New York), 2021-07, Vol.55 (4), p.487-500 [Periódico revisado por pares]

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Título:
Application of Array-Based Oligonucleotides for Synthesis of Genetic Designs
Autor: Sinyakov, A. N. ; Ryabinin, V. A. ; Kostina, E. V.
Assuntos: Biochemistry ; Biomedical and Life Sciences ; Gene libraries ; Human Genetics ; Life Sciences ; Nucleotides ; Oligonucleotides ; Reviews ; Transcription
É parte de: Molecular biology (New York), 2021-07, Vol.55 (4), p.487-500
Descrição: The application of array-based oligonucleotides in biological studies is described. These oligonucleotides are mainly used to design large libraries of various nucleotide sequences, which are applied to study protein-nucleic acid interactions, splicing, transcription, translation, and other regulatory processes in mammalian, yeast, and bacterial systems. The application of gene libraries generated by array-based nucleotides along with advanced methods of the combination of DNA duplexes will make it possible to obtain complex genetic designs for synthetic biology.
Editor: Moscow: Pleiades Publishing
Idioma: Inglês

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