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Natural products as biofuels and bio-based chemicals: fatty acids and isoprenoids

Beller, Harry R ; Lee, Taek Soon ; Katz, Leonard

Natural product reports, 2015-09, Vol.32 (1), p.158-1526 [Periódico revisado por pares]

England

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  • Título:
    Natural products as biofuels and bio-based chemicals: fatty acids and isoprenoids
  • Autor: Beller, Harry R ; Lee, Taek Soon ; Katz, Leonard
  • Assuntos: Alkanes - chemistry ; Alkenes - chemistry ; Biofuels ; Biological Products - chemistry ; Cyclohexenes - chemistry ; Fatty Acids - chemistry ; Hemiterpenes - chemistry ; Molecular Structure ; Sesquiterpenes - chemistry ; Terpenes - chemistry
  • É parte de: Natural product reports, 2015-09, Vol.32 (1), p.158-1526
  • Notas: Leonard Katz earned a B.Sc. at McGill University (Montreal, Canada) and Ph.D. at the University of California, Santa Barbara. After a postdoc and 3 year academic appointment, he spent the next 30 years in the pharma/biotech industry (Schering-Plough, Abbott, Kosan) working on the genetics and biosynthesis of polyketide-based natural products. In 2007, he returned to academia as the Director of Research and Industry Relations at the Synthetic Biology Engineering Research Center (UC Berkeley) where, among other duties, he is involved in employing natural product pathways to generate fuels and chemicals.
    Harry R. Beller earned a B.A. at Wesleyan University (Connecticut), an M.S. at Oregon State University, and a Ph.D. in Civil & Environmental Engineering at Stanford University in 1995. After a postdoctoral fellowship at Stanford University studying benzylsuccinate synthase with Professor Alfred Spormann, he became a Senior Environmental Scientist at Lawrence Livermore National Laboratory in 1998. In 2007, he joined Lawrence Berkeley National Laboratory as a Senior Scientist and Director of Biofuel Pathways at the Joint BioEnergy Institute (JBEI). His work at JBEI has included the development of metabolic pathways for fatty acid-derived biofuels and chemicals.
    Taek Soon Lee earned a B.S. in Chemistry at Seoul National University (Korea) and a Ph.D. in Chemistry at Stanford University in 2006 studying type II aromatic polyketide synthases with Professor Chaitan Khosla. After a postdoctoral training at University of California with Professor Jay D. Keasling, Dr Lee became a Scientist at Lawrence Berkeley National Laboratory in 2008 and joined as a Director of Metabolic Engineering at JBEI. Dr Lee's work at JBEI has included the engineering of metabolic pathways for isoprenoid biofuels and chemicals.
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  • Descrição: Covering: 2005 to 2015 Although natural products are best known for their use in medicine and agriculture, a number of fatty acid-derived and isoprenoid natural products are being developed for use as renewable biofuels and bio-based chemicals. This review summarizes recent work on fatty acid-derived compounds (fatty acid alkyl esters, fatty alcohols, medium- and short-chain methyl ketones, alkanes, α-olefins, and long-chain internal alkenes) and isoprenoids, including hemiterpenes ( e.g. , isoprene and isopentanol), monoterpenes ( e.g. , limonene), and sesquiterpenes ( e.g. , farnesene and bisabolene). We review recent progress in the development of fatty acid-derived and isoprenoid natural products for use as renewable biofuels and bio-based chemicals.
  • Editor: England
  • Idioma: Inglês

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