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0.5 M Gd chelate (Magnevist®) versus 1.0 M Gd chelate (Gadovist®): Dose-independent effect on image quality of pelvic three-dimensional MR-angiography

Goyen, Mathias ; Lauenstein, Thomas C. ; Herborn, Christoph U. ; Debatin, Jörg F. ; Bosk, Silke ; Ruehm, Stefan G.

Journal of magnetic resonance imaging, 2001-11, Vol.14 (5), p.602-607 [Periódico revisado por pares]

New York: John Wiley & Sons, Inc

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Título:
0.5 M Gd chelate (Magnevist®) versus 1.0 M Gd chelate (Gadovist®): Dose-independent effect on image quality of pelvic three-dimensional MR-angiography
Autor: Goyen, Mathias ; Lauenstein, Thomas C. ; Herborn, Christoph U. ; Debatin, Jörg F. ; Bosk, Silke ; Ruehm, Stefan G.
Assuntos: Adult ; Angiography, Digital Subtraction ; comparative studies ; contrast agents ; Contrast Media - administration & dosage ; Female ; Gadolinium ; Gadolinium DTPA - administration & dosage ; Gadovist ; Humans ; Imaging, Three-Dimensional ; Magnetic Resonance Angiography ; Magnevist ; Male ; Middle Aged ; Organometallic Compounds - administration & dosage ; Peripheral Vascular Diseases - diagnosis
É parte de: Journal of magnetic resonance imaging, 2001-11, Vol.14 (5), p.602-607
Notas: ark:/67375/WNG-XG1L54FL-9
ArticleID:JMRI1225
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ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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Descrição: To compare the effect on image quality of a 1.0 M gadolinium (Gd) chelate to that of a conventional 0.5 M Gd chelate, five healthy volunteers and seven patients with angiographically documented aorto‐iliac disease underwent a mono‐station three‐dimensional magnetic resonance angiography (MRA) exam (Siemens SONATA®, Erlangen, Germany) twice, once using Gadovist® 1.0 and the other time using Magnevist® as the contrast agent. All subjects received a fixed volume of Gadovist® 1.0, corresponding to a dose between 0.1 and 0.15 mmol/kg body weight followed by a saline flush. For the Magnevist® exam, the contrast agent volumes and flow rates were doubled. For both quantitative and qualitative analysis of the angiographic data sets, the arterial tree was divided into nine segments. 1 M Gadovist® 1.0‐enhanced three‐dimensional MRA data sets were characterized by significantly higher signal‐to‐noise ratio (SNR) and contrast‐to‐noise ratio (CNR) values compared to 0.5 M Magnevist®‐enhanced images. The data revealed mean SNR/CNR increases exceeding 70% (P < 0.01). Although there was no statistically significant difference in the rating of image quality (P > 0.05), the Gadovist® 1.0 exam led to better delineation of the arterial morphology, especially of small vessels. J. Magn. Reson. Imaging 2001;14:602–607. © 2001 Wiley‐Liss, Inc.
Editor: New York: John Wiley & Sons, Inc
Idioma: Inglês

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0.5 M Gd chelate (Magnevist®) versus 1.0 M Gd chelate (Gadovist®): Dose-independent effect on image quality of pelvic three-dimensional MR-angiography

Goyen, Mathias ; Lauenstein, Thomas C. ; Herborn, Christoph U. ; Debatin, Jörg F. ; Bosk, Silke ; Ruehm, Stefan G.

New York: John Wiley & Sons, Inc

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