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Automated Morphologic Evaluation of Pulmonary Arteries in Primary Pulmonary Hypertension

BOXT, LAWRENCE M ; RICH, STUART ; FRIED, RUTHELLEN ; LA FOLLETTE, LIZELLEN ; SANDOR, TAMAS ; HANLON, WILLIAM B ; HARRINGTON, DONALD P ; REID, LYNNE

Investigative radiology, 1986-12, Vol.21 (12), p.906-909 [Periódico revisado por pares]

United States: Lippincott-Raven Publishers

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  • Título:
    Automated Morphologic Evaluation of Pulmonary Arteries in Primary Pulmonary Hypertension
  • Autor: BOXT, LAWRENCE M ; RICH, STUART ; FRIED, RUTHELLEN ; LA FOLLETTE, LIZELLEN ; SANDOR, TAMAS ; HANLON, WILLIAM B ; HARRINGTON, DONALD P ; REID, LYNNE
  • Assuntos: Humans ; Hypertension, Pulmonary - diagnostic imaging ; Image Processing, Computer-Assisted ; Pulmonary Artery - diagnostic imaging ; Pulmonary Artery - physiopathology ; Pulmonary Wedge Pressure ; Radiography ; Regression Analysis
  • É parte de: Investigative radiology, 1986-12, Vol.21 (12), p.906-909
  • Notas: ObjectType-Article-1
    SourceType-Scholarly Journals-1
    ObjectType-Feature-2
    content type line 23
  • Descrição: Pulmonary wedge angiograms have been shown to reflect the severity of pulmonary vascular disease in congenital heart disease. Thirteen pulmonary wedge angiograms with a balloon occlusion catheter were performed in 11 adult patients (five normals and six with primary pulmonary hypertension [PPH]) and their features related to the resting pulmonary artery pressure (PAP). Individual cine frames from each study were selected and digitized with a computer-assisted operator-interactive program. By fitting densitometric profiles from the vessel segments, serial arterial crosssectional diameters were calculated from mathematically derived points. There was a strong correlation between arterial taper (T, change in vessel caliber per unit axial length) and a power function of mean PAP with T=0.304 × PAP, R = .91,P<.001. These results demonstrate a correlation between an angiographically derived morphologic characteristic of the pulmonary vasculature (taper) and a hemodynamic parameter (PAP) in PPH. This offers a method to follow the course of the disease and the effects of drug therapy by assessing anatomic changes in the vessels.
  • Editor: United States: Lippincott-Raven Publishers
  • Idioma: Inglês
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  • Realização: ABCD-USP USP   Logos de Redes Sociais: Freepik

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