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Hybrid paper-based microfluidics: combination of paper-based analytical device (µPAD) and digital microfluidics (DMF) on a single substrate

Abadian, Arash ; Sepehri Manesh, Samira ; Jafarabadi Ashtiani, Shahin

Microfluidics and nanofluidics, 2017-04, Vol.21 (4), p.1, Article 65 [Periódico revisado por pares]

Berlin/Heidelberg: Springer Berlin Heidelberg

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  • Título:
    Hybrid paper-based microfluidics: combination of paper-based analytical device (µPAD) and digital microfluidics (DMF) on a single substrate
  • Autor: Abadian, Arash ; Sepehri Manesh, Samira ; Jafarabadi Ashtiani, Shahin
  • Assuntos: Analytical Chemistry ; Biomedical Engineering and Bioengineering ; Engineering ; Engineering Fluid Dynamics ; Nanotechnology and Microengineering ; Research Paper
  • É parte de: Microfluidics and nanofluidics, 2017-04, Vol.21 (4), p.1, Article 65
  • Descrição: Microfluidics found its place in point of care diagnostics. Microfluidic devices on paper substrate are proposed on both channel-based and digital microfluidics (DMF). But fluid flow controlling on microfluidics paper-based analytical devices (µPADs) and post-processing on DMF devices have limitations. In this work a new hybrid paper-based device is proposed with the aim of resolving these limitations and expanding the microfluidics capabilities in point of care diagnostics. The hybrid paper-based microfluidics (HPMF) device is composed of a DMF device following a µPAD in a single substrate, in which the DMF part performs the preprocessing steps of the test on droplets and transfers the resulting droplet to the µPAD part of the device for post-processing steps. The fabrication process of the device is rapid and very low cost due to use of paper substrate and out of clean-room processes. The results show that the proposed HPMF device can perform droplet operations: moving, mixing, and splitting.
  • Editor: Berlin/Heidelberg: Springer Berlin Heidelberg
  • Idioma: Inglês
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  • Realização: ABCD-USP USP   Logos de Redes Sociais: Freepik

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