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Towards a consensus on how to diagnose and quantify female pattern hair loss - The 'Female Pattern Hair Loss Severity Index (FPHL-SI)'

Harries, M. ; Tosti, A. ; Bergfeld, W. ; Blume-Peytavi, U. ; Shapiro, J. ; Lutz, G. ; Messenger, A. ; Sinclair, R. ; Paus, R.

Journal of the European Academy of Dermatology and Venereology, 2016-04, Vol.30 (4), p.667-676 [Periódico revisado por pares]

England: Blackwell Publishing Ltd

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  • Título:
    Towards a consensus on how to diagnose and quantify female pattern hair loss - The 'Female Pattern Hair Loss Severity Index (FPHL-SI)'
  • Autor: Harries, M. ; Tosti, A. ; Bergfeld, W. ; Blume-Peytavi, U. ; Shapiro, J. ; Lutz, G. ; Messenger, A. ; Sinclair, R. ; Paus, R.
  • Assuntos: Alopecia - classification ; Alopecia - diagnosis ; Female ; Humans ; Severity of Illness Index
  • É parte de: Journal of the European Academy of Dermatology and Venereology, 2016-04, Vol.30 (4), p.667-676
  • Notas: ark:/67375/WNG-N63NQ6G1-H
    ArticleID:JDV13455
    istex:AD9D2776B80D335C41DFAA8485FA85A995F362DC
    Dr Kurt Wolff
    Conflicts of interest
    All authors serve as consultants for competing commercial entities with an interest in treating or preventing hair loss and therefore have strived to reach a consensus that has the potential of meeting universal approval among experts in the field. The sponsor had no influence on the contents of this consensus paper, which solely expresses the opinion of its authors
    Correction added on 09 February 2016 after first online publication; The affiliation of the second author A. Tosti has been corrected.
    M. Harries ORCID is 0000‐0002‐0563‐8690.
    The Edinburgh consensus meeting, its transcription, and the generation of the corresponding manuscript were supported by an educational grant from Dr Kurt Wolff, Bielefeld, Germany.
    Funding source
    ObjectType-Article-1
    SourceType-Scholarly Journals-1
    ObjectType-Feature-2
  • Descrição: Background Female pattern hair loss (FPHL) is a common non‐scarring alopecia characterized by widening of the midline hair part at the crown (vertex). In 1977, Ludwig developed a scale that graded the degree of visible vertex hair thinning from I (least severe) to III (most severe). However, by the time patients exhibit the full manifestations of ‘Ludwig I’, they have already lost a significant volume of hair. Although current therapies may realistically halt progression of hair loss, improvements in hair density is often more limited. Identification and grading of FPHL at an earlier stage is desirable to institute appropriate therapy before significant hair loss has occurred and to enable monitoring over time. Aim To generate consensus guidance for the recognition and quantification of FPHL that can be used in the clinic. Methods Nine clinicians from Europe, North America and Australia experienced in the management of FPHL developed this scale by consensus. Results We propose a three‐point severity scale (termed the FPHL Severity Index (FPHL‐SI)) that combines validated measures of hair shedding, midline hair density and scalp trichoscopy criteria to produce a total FPHL‐SI score (maximum score = 20). The score is designed to grade FPHL severity over time, while being sufficiently sensitive to identify early disease. A score of 0–4 makes FPHL unlikely; a score of 5–9 would indicate early‐stage FPHL, with higher scores indicating greater disease severity. Conclusions As a starting point for further public debate, we employ criteria already used in clinical practice to generate a pragmatic FPHL grading system (FPHL‐SI) of sufficient sensitivity to identify and monitor early FPHL changes. This may have to be further optimized after systematic validation in clinical practice.
  • Editor: England: Blackwell Publishing Ltd
  • Idioma: Inglês
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  • Realização: ABCD-USP USP   Logos de Redes Sociais: Freepik

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