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Chemogenomics in drug discovery a medicinal chemistry perspective

Hugo Kubinyi; Gerhard Müller 1963-

Weinheim Wiley-VCH c2004

Localização: CQ - Conjunto das Químicas    (615.19 C5173 ) e outros locais(Acessar)

  • Título:
    Chemogenomics in drug discovery a medicinal chemistry perspective
  • Autor: Hugo Kubinyi; Gerhard Müller 1963-
  • Assuntos: Pharmaceutical chemistry; Drug development; Pharmacogenetics; Combinatorial Chemistry Techniques; Drug Design; Genomics; PLANEJAMENTO DE FÁRMACOS; QUÍMICA FARMACÊUTICA; FARMACOGENÉTICA; GENOMAS
  • Notas: Includes bibliographical references and index
  • Descrição: Target family-directed masterkeyes in chemogenomics Drug discovery from side effects The value of chemical genetics in drug discovery Structural aspects of binding site similarity: a 3D upgrade for chemogenomics The contribution of molecular informatics to chemogenomics: knowledge-based discovery of biological targets and chemical lead compounds Chemical kinomics Structural aspects of kinases and their inhibitors A chemical genomics approach for ion channel modulators Phosphodiesterase inhibitors: a chemogenomic view Proteochemometrics: a tool for modeling the molecular interaction space Some principles related to chemogenomics in compound library and template design for GPCRs Computational filters in lead generation: targeting drug-like chemotypes Navigation in chemical space: ligand-based design of focused compound libraries Natural product-derived compound libraries and protein structure similarity as guiding principles for
    the discovery of drug candidates Combinatorial chemistry in the age of chemical genomics
  • Títulos relacionados: Série:Methods and principles in medicinal chemistry ; v. 22
  • Editor: Weinheim Wiley-VCH
  • Data de criação/publicação: c2004
  • Formato: xxiv, 463 p ill. (some col.) 25 cm.
  • Idioma: Inglês
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  • Realização: ABCD-USP USP   Logos de Redes Sociais: Freepik

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