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Synthesis of S-aminoalkyl derivatives of 1,2,4-triazino[5,6-b]indole

Lopatik, D. V. ; Kuvaeva, Z. I. ; Naidenov, V. E. ; Bondareva, O. M. ; Tychinskaya, L. Yu

Proceedings of the National Academy of Sciences of Belarus, Chemical Series, 2021-09, Vol.57 (3), p.294-299 [Periódico revisado por pares]

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Título:
Synthesis of S-aminoalkyl derivatives of 1,2,4-triazino[5,6-b]indole
Autor: Lopatik, D. V. ; Kuvaeva, Z. I. ; Naidenov, V. E. ; Bondareva, O. M. ; Tychinskaya, L. Yu
É parte de: Proceedings of the National Academy of Sciences of Belarus, Chemical Series, 2021-09, Vol.57 (3), p.294-299
Descrição: Condensed indole derivatives of the 1,2,4-triazino[5,6-b]indole group show high biological activity and are of interest for the development of pharmaceuticals that have antihypoxic and antisurditant effects. By S-aminoalkylation reactions on a thione group, S-aminoalkyl derivatives of 1,2,4-triazino[5,6-b]indole-3-thione that were subject to hydrobromination in order to obtain the form of hydrobromides were synthesized, isolated and characterized.
Idioma: Inglês

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