skip to main content
Idioma:
Primo Search
Clear Search Box
Search in: Busca Geral
Busca Avançada
Busca por Índices

Bioactive (3Z,5E)-11,20-Epoxybriara-3,5-dien-7,18-olide Diterpenoids from the South China Sea Gorgonian Dichotella gemmacea

Cui Li ; Ming-Ping La ; Peng Sun ; Tibor Kurtan ; Attila Mandi ; Hua Tang ; Bao-Shu Liu ; Yang-Hua Yi ; Ling Li ; Wen Zhang

Molecular Diversity Preservation International 2011

Sem texto completo

Citações Citado por
  • Título:
    Bioactive (3Z,5E)-11,20-Epoxybriara-3,5-dien-7,18-olide Diterpenoids from the South China Sea Gorgonian Dichotella gemmacea
  • Autor: Cui Li ; Ming-Ping La ; Peng Sun ; Tibor Kurtan ; Attila Mandi ; Hua Tang ; Bao-Shu Liu ; Yang-Hua Yi ; Ling Li ; Wen Zhang
  • Assuntos: biological activity ; briarane diterpenoids ; Dichotella gemmacea ; gorgonian ; structure elucidation
  • Notas: http://www.doaj.org/doaj?func=openurl&genre=article&issn=16603397&date=2011&volume=9&issue=8&spage=1403
    http://www.mdpi.com/1660-3397/9/8/1403/
  • Descrição: Six new (3Z,5E)-11,20-epoxybriara-3,5-dien-7,18-olide diterpenoids, gemmacolides N–S (1–6), were isolated together with four known analogues, juncenolide D, and juncins R, S and U (7–10), from the South China Sea gorgonian Dichotella gemmacea. The structures of the new compounds were elucidated by the detailed analysis of spectroscopic data in combination with the comparison with reported data. The absolute configuration of 1 was determined by a TDDFT calculation of its solution ECD spectrum, affording the determination of absolute configuration of other analogues by simply comparing their ECD spectra with that of 1. The cytotoxic and antimicrobial activities of these compounds were evaluated. In preliminary in vitro bioassays, compounds 4, 5, 6, 8 and 9 showed cytotoxicity against A549 and MG63, while compounds 1, 2, 4, 7–10 showed antimicrobial activity against the fungus Septoria tritici and the bacterium Escherichia coli.
  • Editor: Molecular Diversity Preservation International
  • Data de criação/publicação: 2011
  • Idioma: Inglês
Voltar para lista de resultados

  • Realização: ABCD-USP USP   Logos de Redes Sociais: Freepik

Buscando em bases de dados remotas. Favor aguardar.