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Synthetic biology strategies for improving microbial synthesis of “green” biopolymers

Anderson, Lisa A. ; Islam, M. Ahsanul ; Prather, Kristala L.J.

The Journal of biological chemistry, 2018-04, Vol.293 (14), p.5053-5061 [Periódico revisado por pares]

United States: Elsevier Inc

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Título:
Synthetic biology strategies for improving microbial synthesis of “green” biopolymers
Autor: Anderson, Lisa A. ; Islam, M. Ahsanul ; Prather, Kristala L.J.
Assuntos: Bacteria - chemistry ; Bacteria - genetics ; Bacteria - metabolism ; biomaterials ; Biosynthetic Pathways ; Fungi - chemistry ; Fungi - genetics ; Fungi - metabolism ; Green Chemistry Technology - methods ; Industrial Microbiology - methods ; metabolic engineering ; Metabolic Engineering - methods ; polysaccharide ; Polysaccharides - chemistry ; Polysaccharides - genetics ; Polysaccharides - metabolism ; secretion ; synthetic biology ; Synthetic Biology - methods ; Thematic Minireviews
É parte de: The Journal of biological chemistry, 2018-04, Vol.293 (14), p.5053-5061
Notas: ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-2
Edited by Joseph M. Jez
Present address: Dept. of Chemical Engineering, Loughborough University, Loughborough, Leicestershire LE11 3TU, United Kingdom.
Descrição: Polysaccharide-based biopolymers have many material properties relevant to industrial and medical uses, including as drug delivery agents, wound-healing adhesives, and food additives and stabilizers. Traditionally, polysaccharides are obtained from natural sources. Microbial synthesis offers an attractive alternative for sustainable production of tailored biopolymers. Here, we review synthetic biology strategies for select “green” biopolymers: cellulose, alginate, chitin, chitosan, and hyaluronan. Microbial production pathways, opportunities for pathway yield improvements, and advances in microbial engineering of biopolymers in various hosts are discussed. Taken together, microbial engineering has expanded the repertoire of green biological chemistry by increasing the diversity of biobased materials.
Editor: United States: Elsevier Inc
Idioma: Inglês

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Synthetic biology strategies for improving microbial synthesis of “green” biopolymers

Anderson, Lisa A. ; Islam, M. Ahsanul ; Prather, Kristala L.J.

United States: Elsevier Inc

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