Idioma:

Patient and general population values for luminal and perianal fistulising Crohn's disease health states

Rencz, Fanni ; Stalmeier, Peep F. M. ; Péntek, Márta ; Brodszky, Valentin ; Ruzsa, Gábor ; Gönczi, Lóránt ; Palatka, Károly ; Herszényi, László ; Schäfer, Eszter ; Banai, János ; Rutka, Mariann ; Gulácsi, László ; Lakatos, Peter L.

The European journal of health economics, 2019-06, Vol.20 (Suppl 1), p.S91-S100 [Periódico revisado por pares]

Berlin/Heidelberg: Springer

Texto completo disponível

Citações Citado por

Enviar para

Título:
Patient and general population values for luminal and perianal fistulising Crohn's disease health states
Autor: Rencz, Fanni ; Stalmeier, Peep F. M. ; Péntek, Márta ; Brodszky, Valentin ; Ruzsa, Gábor ; Gönczi, Lóránt ; Palatka, Károly ; Herszényi, László ; Schäfer, Eszter ; Banai, János ; Rutka, Mariann ; Gulácsi, László ; Lakatos, Peter L.
Assuntos: Adolescent ; Adult ; Age Factors ; Anus Diseases - etiology ; Anus Diseases - pathology ; Anus Diseases - psychology ; Crohn Disease - complications ; Crohn Disease - pathology ; Crohn Disease - psychology ; Crohns disease ; Cross-Sectional Studies ; Digestive System Fistula - etiology ; Digestive System Fistula - pathology ; Digestive System Fistula - psychology ; Economic Policy ; Female ; Fistula ; Health Care Management ; Health Economics ; Humans ; Male ; Medicine ; Medicine & Public Health ; Middle Aged ; Original Paper ; Pharmacoeconomics and Health Outcomes ; Public Finance ; Public Health ; Quality of Life - psychology ; Severity of Illness Index ; Sex Factors ; Socioeconomic Factors ; Tradeoff analysis ; Young Adult
É parte de: The European journal of health economics, 2019-06, Vol.20 (Suppl 1), p.S91-S100
Notas: ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
Descrição: Background In patients with Crohn's disease (CD), luminal disease activity paralleled by perianal fistulas may seriously impair health-related quality of life (HRQoL). Health utility values are not available from patients with CD that reflect the health loss associated with both luminal and perianal CD. Objective To generate utilities for luminal and concomitant perianal fistulising CD health states directly from patients and from members of the general public. Methods A cross-sectional survey was undertaken enrolling CD patients and a convenience sample of members of the general population. Respondents were asked to evaluate four common CD heath states [severe luminal disease (sCD), mild luminal disease (mCD), severe luminal disease with active perianal fistulas (sPFCD), and mild luminal disease with active perianal fistulas (mPFCD)] by 10-year time trade-off (TTO). In addition, patients assessed their current HRQoL by the TTO method. Results Responses of 206 patients (40.8% with perianal fistulas) and 221 members of the general population were analysed. Mean±SD utilities among patients for sPFCD, sCD, mPFCD and mCD states were 0.69±0.33, 0.73 ±0.31,0.80±0.29 and 0.87 ±0.26. Corresponding values in the general public were: 0.59 ±0.31, 0.65 ±0.29, 0.80±0.26 and 0.88 ±0.25. Patients with active perianal fistulas, previous non-resection surgeries, and higher pain intensity scores valued their current health as worse (p < 0.05). Conclusions TTO is a feasible method to assess HRQoL in patients with perianal fistulising disease, often not captured by health status questionnaires. Utilities from this study are intended to support the optimization of treatment-related decision making in patients with luminal disease paralleled by active perianal fistulas.
Editor: Berlin/Heidelberg: Springer
Idioma: Inglês

Links

View this record in MEDLINE/PubMed

Voltar para lista de resultados

Realização: Logos de Redes Sociais:

Patient and general population values for luminal and perianal fistulising Crohn's disease health states

Rencz, Fanni ; Stalmeier, Peep F. M. ; Péntek, Márta ; Brodszky, Valentin ; Ruzsa, Gábor ; Gönczi, Lóránt ; Palatka, Károly ; Herszényi, László ; Schäfer, Eszter ; Banai, János ; Rutka, Mariann ; Gulácsi, László ; Lakatos, Peter L.

Berlin/Heidelberg: Springer

Buscando em bases de dados remotas. Favor aguardar.