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Expression of alpha-melanocyte-stimulating hormone mRNA and its significance in human skin autografts

Xue, Chunyu ; Xing, Xin ; Li, Li

Zhongguo xiu fu chong jian wai ke za zhi, 2006-05, Vol.20 (5), p.491-494 [Periódico revisado por pares]

China

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  • Título:
    Expression of alpha-melanocyte-stimulating hormone mRNA and its significance in human skin autografts
  • Autor: Xue, Chunyu ; Xing, Xin ; Li, Li
  • Assuntos: Adolescent ; Adult ; alpha-MSH - genetics ; Child ; Female ; Humans ; Male ; Neck ; Reverse Transcriptase Polymerase Chain Reaction ; RNA, Messenger - genetics ; Skin - metabolism ; Skin Pigmentation - genetics ; Skin Transplantation ; Transplantation, Autologous
  • É parte de: Zhongguo xiu fu chong jian wai ke za zhi, 2006-05, Vol.20 (5), p.491-494
  • Notas: ObjectType-Article-2
    SourceType-Scholarly Journals-1
    ObjectType-Feature-1
    content type line 23
  • Descrição: To discuss the expression of alpha-melanocyte-stimulating hormone (alpha-MSH) mRNA in human medium thickness skin autografts and to investigate the role of alpha-MSH in hyperpigmented process of skin autografts. The samples were from medium thickness skin autografts on neck of the patients after 1 year of surgery. The size of sample was about 1.0 cm X 0.5 cm. RT-PCR technique was performed to detect the expression of alpha-MSH mRNA in medium thickness skin autografts and normal skin respectively. Masson-Fontana stain technique was performed to detect the contents of melanin in medium thickness skin autografts and normal skin epidermis respectively. The expression of alpha-MSH mRNA in medium thickness skin autografts was much stronger than that in control normal skin, showing statistically significant difference (P<0.01). The expression of alpha-MSH/beta2-microglobulin mRNA in normal skin of donor area was no statistically significant differences compared with normal skin around recipient area. The contents of
  • Editor: China
  • Idioma: Chinês
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  • Realização: ABCD-USP USP   Logos de Redes Sociais: Freepik

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