Idioma:

Effects of a Phonologically Driven Treatment for Dyslexia on Lactate Levels Measured by Proton MR Spectroscopic Imaging

Richards, Todd L ; Corina, David ; Serafini, Sandra ; Steury, Keith ; Echelard, Denise R ; Dager, Stephen R ; Marro, Ken ; Abbott, Robert D ; Maravilla and, Kenneth R ; Berninger, Virginia W

American journal of neuroradiology : AJNR, 2000-05, Vol.21 (5), p.916-922 [Periódico revisado por pares]

Oak Brook, IL: Am Soc Neuroradiology

Texto completo disponível

Citações Citado por

Enviar para

Título:
Effects of a Phonologically Driven Treatment for Dyslexia on Lactate Levels Measured by Proton MR Spectroscopic Imaging
Autor: Richards, Todd L ; Corina, David ; Serafini, Sandra ; Steury, Keith ; Echelard, Denise R ; Dager, Stephen R ; Marro, Ken ; Abbott, Robert D ; Maravilla and, Kenneth R ; Berninger, Virginia W
Assuntos: Biological and medical sciences ; Brain ; Brain - physiopathology ; Child ; Disorders of higher nervous function. Focal brain diseases. Central vestibular syndrome and deafness. Brain stem syndromes ; Dyslexia - diagnosis ; Dyslexia - physiopathology ; Dyslexia - therapy ; Follow-Up Studies ; Humans ; Lactic Acid - metabolism ; Magnetic Resonance Imaging ; Magnetic Resonance Spectroscopy ; Male ; Medical sciences ; Nervous system (semeiology, syndromes) ; Neurology ; Phonetics ; Remedial Teaching ; Treatment Outcome
É parte de: American journal of neuroradiology : AJNR, 2000-05, Vol.21 (5), p.916-922
Notas: ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
Descrição: Dyslexia is a language disorder in which reading ability is compromised because of poor phonologic skills. The purpose of this study was to measure the effect of a phonologically driven treatment for dyslexia on brain lactate response to language stimulation as measured by proton MR spectroscopic imaging. Brain lactate metabolism was measured at two different time points (1 year apart) during four different cognitive tasks (three language tasks and one nonlanguage task) in dyslexic participants (n = 8) and in control participants (n = 7) by using a fast MR spectroscopic imaging technique called proton echo-planar spectroscopic imaging (1 cm3 voxel resolution). The age range for both dyslexic and control participants was 10 to 13 years. Between the first and second imaging sessions, the dyslexic boys participated in an instructional intervention, which was a reading/science workshop. Before treatment, the dyslexic boys showed significantly greater lactate elevation compared with a control group in the left anterior quadrant (analysis of variance, P = .05) of the brain during a phonologic task. After treatment, however, brain lactate elevation was not significantly different from that of the control group in the left anterior quadrant during the same phonologic task. Behaviorally, the dyslexic participants improved in the phonologic aspects of reading. Instructional intervention that improved phonologic performance in dyslexic boys was associated with changes in brain lactate levels as measured by proton echo-planar spectroscopic imaging.
Editor: Oak Brook, IL: Am Soc Neuroradiology
Idioma: Inglês

Links

Voltar para lista de resultados

Realização: Logos de Redes Sociais:

Effects of a Phonologically Driven Treatment for Dyslexia on Lactate Levels Measured by Proton MR Spectroscopic Imaging

Richards, Todd L ; Corina, David ; Serafini, Sandra ; Steury, Keith ; Echelard, Denise R ; Dager, Stephen R ; Marro, Ken ; Abbott, Robert D ; Maravilla and, Kenneth R ; Berninger, Virginia W

Oak Brook, IL: Am Soc Neuroradiology

Buscando em bases de dados remotas. Favor aguardar.