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Interaction with Cellular CD4 Exposes HIV-1 Envelope Epitopes Targeted by Antibody-Dependent Cell-Mediated Cytotoxicity

Veillette, Maxime ; Désormeaux, Anik ; Medjahed, Halima ; Gharsallah, Nour-Elhouda ; Coutu, Mathieu ; Baalwa, Joshua ; Guan, Yongjun ; Lewis, George ; Ferrari, Guido ; Hahn, Beatrice H. ; Haynes, Barton F. ; Robinson, James E. ; Kaufmann, Daniel E. ; Bonsignori, Mattia ; Sodroski, Joseph ; Finzi, Andrés Silvestri, G.

Journal of Virology, 2014-03, Vol.88 (5), p.2633-2644 [Periódico revisado por pares]

United States: American Society for Microbiology

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Título:
Interaction with Cellular CD4 Exposes HIV-1 Envelope Epitopes Targeted by Antibody-Dependent Cell-Mediated Cytotoxicity
Autor: Veillette, Maxime ; Désormeaux, Anik ; Medjahed, Halima ; Gharsallah, Nour-Elhouda ; Coutu, Mathieu ; Baalwa, Joshua ; Guan, Yongjun ; Lewis, George ; Ferrari, Guido ; Hahn, Beatrice H. ; Haynes, Barton F. ; Robinson, James E. ; Kaufmann, Daniel E. ; Bonsignori, Mattia ; Sodroski, Joseph ; Finzi, Andrés
Silvestri, G.
Assuntos: Antibody-Dependent Cell Cytotoxicity - immunology ; CD4 Antigens - chemistry ; CD4 Antigens - immunology ; CD4 Antigens - metabolism ; CD4-Positive T-Lymphocytes - immunology ; CD4-Positive T-Lymphocytes - virology ; Cell Line ; env Gene Products, Human Immunodeficiency Virus - chemistry ; env Gene Products, Human Immunodeficiency Virus - immunology ; env Gene Products, Human Immunodeficiency Virus - metabolism ; Epitopes, T-Lymphocyte - immunology ; Epitopes, T-Lymphocyte - metabolism ; HIV Antibodies - immunology ; HIV Antibodies - metabolism ; HIV Infections - immunology ; HIV Infections - metabolism ; HIV-1 - immunology ; Human immunodeficiency virus 1 ; Human immunodeficiency virus 2 ; Human Immunodeficiency Virus Proteins - immunology ; Human Immunodeficiency Virus Proteins - metabolism ; Humans ; Models, Molecular ; nef Gene Products, Human Immunodeficiency Virus - immunology ; nef Gene Products, Human Immunodeficiency Virus - metabolism ; Pathogenesis and Immunity ; Protein Binding - immunology ; Protein Conformation ; Protein Interaction Domains and Motifs ; Protein Multimerization ; Viral Regulatory and Accessory Proteins - immunology ; Viral Regulatory and Accessory Proteins - metabolism
É parte de: Journal of Virology, 2014-03, Vol.88 (5), p.2633-2644
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M.V. and A.D. contributed equally to this article.
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Editor: United States: American Society for Microbiology
Idioma: Inglês

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Interaction with Cellular CD4 Exposes HIV-1 Envelope Epitopes Targeted by Antibody-Dependent Cell-Mediated Cytotoxicity

United States: American Society for Microbiology

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