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Management of esophageal neoplasms by endoscopic submucosal dissection: experience over 100 consecutive procedures

Josué Aliaga Ramos ; Yoshinori Morita ; Takashi Toyonaga ; Danilo Carvalho ; Moises Salgado Pedrosa ; Vitor N. Arantes

Clinical endoscopy, 2023-09, Vol.56 (5), p.613-622 [Periódico revisado por pares]

대한소화기내시경학회

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  • Título:
    Management of esophageal neoplasms by endoscopic submucosal dissection: experience over 100 consecutive procedures
  • Autor: Josué Aliaga Ramos ; Yoshinori Morita ; Takashi Toyonaga ; Danilo Carvalho ; Moises Salgado Pedrosa ; Vitor N. Arantes
  • Assuntos: Early esophageal cancer ; Endoscopic submucosal dissection ; Superficial esophageal neoplasms
  • É parte de: Clinical endoscopy, 2023-09, Vol.56 (5), p.613-622
  • Notas: The Korean Society of Gastrointestinal Endoscopy
  • Descrição: Background/Aims: Endoscopic submucosal dissection (ESD) is currently considered the first-line treatment for the eradication of superficial neoplasms of the esophagus in Eastern countries. However, in the West, particularly in Latin America, the experience with esophageal ESD is still limited because of the high technical complexity required for its execution. This study aimed to present the results of the clinical application of ESD to manage superficial esophageal neoplasms in a Latin American center in over 100 consecutive cases. Methods: This retrospective study included consecutive patients who underwent endoscopic ESD for superficial esophageal neoplasms between 2009 and 2022. The following clinical outcomes were assessed: en bloc, complete, and curative resection rates, local recurrence, adverse events, and procedure-related mortality. Results: Esophageal ESD was performed mainly for squamous cell carcinoma (66.6%), high-grade intraepithelial neoplasia (17.1%), and adenocarcinoma (11.4%). En bloc and complete resection rates were 96.2% and 81.0%, respectively. The curative resection rate was 64.8%. Adverse events occurred in six cases (5.7%). Endoscopic follow-up was performed for an average period of 29.7 months. Conclusions: ESD performed by trained operators is feasible, safe, and clinically effective for managing superficial neoplastic lesions of the esophagus in Latin America.
  • Editor: 대한소화기내시경학회
  • Idioma: Coreano
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  • Realização: ABCD-USP USP   Logos de Redes Sociais: Freepik

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