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Comparative genomic analysis of eutherian ribonuclease A genes
Premzl, Marko
Molecular genetics and genomics : MGG, 2014-04, Vol.289 (2), p.161-167
[Periódico revisado por pares]
Berlin/Heidelberg: Springer-Verlag
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Título:
Comparative genomic analysis of eutherian ribonuclease A genes
Autor:
Premzl, Marko
Assuntos:
Animal Genetics and Genomics
;
Animals
;
Biochemistry
;
Biomedical and Life Sciences
;
data collection
;
Evolution, Molecular
;
Genome
;
Genomics
;
Human Genetics
;
Life Sciences
;
major genes
;
Mammals - genetics
;
Microbial Genetics and Genomics
;
Molecular Sequence Annotation
;
multigene family
;
Original Paper
;
Phylogeny
;
Plant Genetics and Genomics
;
promoter regions
;
Ribonuclease, Pancreatic - classification
;
Ribonuclease, Pancreatic - genetics
;
ribonucleases
É parte de:
Molecular genetics and genomics : MGG, 2014-04, Vol.289 (2), p.161-167
Notas:
http://dx.doi.org/10.1007/s00438-013-0801-5
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SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
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Descrição:
The present study attempted to update comprehensive eutherian ribonuclease A gene data sets, using public eutherian genomic sequence data sets and new genomics and molecular evolution tests. Among 448 ribonuclease A potential coding sequences, the present analysis annotated 255 complete coding sequences. The most comprehensive data set of eutherian ribonuclease A genes first characterized 13 major gene clusters, 9 of which showed evidence of differential gene expansions. In addition, the present analysis described common predicted promoter regions of eutherian ribonuclease A genes. The present study also attempted to resolve discrepancies in descriptions of eutherian ribonuclease A genes. Thus, the integrated gene annotations, phylogenetic analysis and protein molecular evolution analysis proposed new classification and nomenclature of eutherian ribonuclease A genes, as new framework of future experiments.
Editor:
Berlin/Heidelberg: Springer-Verlag
Idioma:
Inglês
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