Idioma:

Risk factors for Covid-19 severity and fatality: a structured literature review

Wolff, Dominik ; Nee, Sarah ; Hickey, Natalie Sandy ; Marschollek, Michael

Infection, 2021-02, Vol.49 (1), p.15-28 [Periódico revisado por pares]

Berlin/Heidelberg: Springer Berlin Heidelberg

Texto completo disponível

Citações Citado por

Enviar para

Título:
Risk factors for Covid-19 severity and fatality: a structured literature review
Autor: Wolff, Dominik ; Nee, Sarah ; Hickey, Natalie Sandy ; Marschollek, Michael
Assuntos: Age Factors ; Coagulation ; Comorbidity ; Coronaviruses ; COVID-19 ; COVID-19 - epidemiology ; COVID-19 - mortality ; COVID-19 - pathology ; COVID-19 - virology ; Diabetes mellitus ; Diabetes Mellitus - epidemiology ; Diabetes Mellitus - mortality ; Diabetes Mellitus - pathology ; Diabetes Mellitus - virology ; Disseminated Intravascular Coagulation - epidemiology ; Disseminated Intravascular Coagulation - mortality ; Disseminated Intravascular Coagulation - pathology ; Disseminated Intravascular Coagulation - virology ; Family Medicine ; General Practice ; Health care ; Health risks ; Heart - physiopathology ; Heart - virology ; Hospitalization - statistics & numerical data ; Humans ; Hypertension ; Hypertension - epidemiology ; Hypertension - mortality ; Hypertension - pathology ; Hypertension - virology ; Infectious Diseases ; Internal Medicine ; Kidney - pathology ; Kidney - virology ; Literature reviews ; Liver - pathology ; Liver - virology ; Medicine ; Medicine & Public Health ; Obesity - epidemiology ; Obesity - mortality ; Obesity - pathology ; Obesity - virology ; Pandemics ; Public health ; Review ; Risk analysis ; Risk Factors ; SARS-CoV-2 ; SARS-CoV-2 - pathogenicity ; Severity of Illness Index ; Survival Analysis ; Tuberculosis ; Tuberculosis, Pulmonary - epidemiology ; Tuberculosis, Pulmonary - mortality ; Tuberculosis, Pulmonary - pathology ; Tuberculosis, Pulmonary - virology ; Vaccines
É parte de: Infection, 2021-02, Vol.49 (1), p.15-28
Notas: ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ObjectType-Undefined-3
Descrição: Purpose Covid-19 is a global threat that pushes health care to its limits. Since there is neither a vaccine nor a drug for Covid-19, people with an increased risk for severe and fatal courses of disease particularly need protection. Furthermore, factors increasing these risks are of interest in the search of potential treatments. A systematic literature review on the risk factors of severe and fatal Covid-19 courses is presented. Methods The review is carried out on PubMed and a publicly available preprint dataset. For analysis, risk factors are categorized and information regarding the study such as study size and location are extracted. The results are compared to risk factors listed by four public authorities from different countries. Results The 28 records included, eleven of which are preprints, indicate that conditions and comorbidities connected to a poor state of health such as high age, obesity, diabetes and hypertension are risk factors for severe and fatal disease courses. Furthermore, severe and fatal courses are associated with organ damages mainly affecting the heart, liver and kidneys. Coagulation dysfunctions could play a critical role in the organ damaging. Time to hospital admission, tuberculosis, inflammation disorders and coagulation dysfunctions are identified as risk factors found in the review but not mentioned by the public authorities. Conclusion Factors associated with increased risk of severe or fatal disease courses were identified, which include conditions connected with a poor state of health as well as organ damages and coagulation dysfunctions. The results may facilitate upcoming Covid-19 research.
Editor: Berlin/Heidelberg: Springer Berlin Heidelberg
Idioma: Inglês

Links

View this record in MEDLINE/PubMed

Voltar para lista de resultados

Realização: Logos de Redes Sociais:

Risk factors for Covid-19 severity and fatality: a structured literature review

Wolff, Dominik ; Nee, Sarah ; Hickey, Natalie Sandy ; Marschollek, Michael

Berlin/Heidelberg: Springer Berlin Heidelberg

Buscando em bases de dados remotas. Favor aguardar.