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HPV Vaccine against Anal HPV Infection and Anal Intraepithelial Neoplasia

Palefsky, Joel M ; Giuliano, Anna R ; Goldstone, Stephen ; Moreira, Edson D ; Aranda, Carlos ; Jessen, Heiko ; Hillman, Richard ; Ferris, Daron ; Coutlee, Francois ; Stoler, Mark H ; Marshall, J. Brooke ; Radley, David ; Vuocolo, Scott ; Haupt, Richard M ; Guris, Dalya ; Garner, Elizabeth I.O

The New England journal of medicine, 2011-10, Vol.365 (17), p.1576-1585 [Periódico revisado por pares]

Waltham, MA: Massachusetts Medical Society

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Título:
HPV Vaccine against Anal HPV Infection and Anal Intraepithelial Neoplasia
Autor: Palefsky, Joel M ; Giuliano, Anna R ; Goldstone, Stephen ; Moreira, Edson D ; Aranda, Carlos ; Jessen, Heiko ; Hillman, Richard ; Ferris, Daron ; Coutlee, Francois ; Stoler, Mark H ; Marshall, J. Brooke ; Radley, David ; Vuocolo, Scott ; Haupt, Richard M ; Guris, Dalya ; Garner, Elizabeth I.O
Assuntos: Adolescent ; Adult ; Anal cancer ; Anus Diseases - prevention & control ; Anus Diseases - virology ; Anus Neoplasms - prevention & control ; Anus Neoplasms - virology ; Biological and medical sciences ; Biomedical research ; Cancer ; Carcinoma in Situ - prevention & control ; Carcinoma in Situ - virology ; Cervical cancer ; Double-Blind Method ; Drug therapy ; Gays & lesbians ; General aspects ; Human papillomavirus ; Human papillomavirus 11 ; Human papillomavirus 16 ; Human papillomavirus 18 ; Human papillomavirus 6 ; Human Papillomavirus Recombinant Vaccine Quadrivalent, Types 6, 11, 16, 18 ; Humans ; Infections ; Male ; Medical sciences ; Men ; Mens health ; Motivation ; Papillomavirus infections ; Papillomavirus Infections - prevention & control ; Papillomavirus Vaccines ; Prevention ; Prevention and actions ; Public health. Hygiene ; Public health. Hygiene-occupational medicine ; Sex ; Vaccines ; Womens health ; Young Adult
É parte de: The New England journal of medicine, 2011-10, Vol.365 (17), p.1576-1585
Notas: ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-News-2
ObjectType-Feature-3
content type line 23
Descrição: Infection with human papillomavirus (HPV) serotypes 16 and 18 in men who have sex with men is a cause of considerable morbidity associated with anal intraepithelial neoplasia. This study shows that the HPV vaccine decreases the risk of HPV-associated anal disease. Anal cancer is biologically similar to cervical cancer, including having a causal relationship with human papillomavirus (HPV) infection. 1 Although HPV type 6 (HPV-6) or HPV type 11 (HPV-11) alone is rarely causal, the proportion of anal cancers associated with infection with HPV type 16 (HPV-16) or HPV type 18 (HPV-18) is as high as or higher than the proportion of cervical cancers. 1 Just as cervical cancer is preceded by high-grade cervical intraepithelial neoplasia (grade ≥2), anal cancer is preceded by high-grade anal intraepithelial neoplasia (grade 2 or 3). 2 – 4 Although not yet formally demonstrated, prevention or treatment of high-grade anal . . .
Editor: Waltham, MA: Massachusetts Medical Society
Idioma: Inglês

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HPV Vaccine against Anal HPV Infection and Anal Intraepithelial Neoplasia

Palefsky, Joel M ; Giuliano, Anna R ; Goldstone, Stephen ; Moreira, Edson D ; Aranda, Carlos ; Jessen, Heiko ; Hillman, Richard ; Ferris, Daron ; Coutlee, Francois ; Stoler, Mark H ; Marshall, J. Brooke ; Radley, David ; Vuocolo, Scott ; Haupt, Richard M ; Guris, Dalya ; Garner, Elizabeth I.O

Waltham, MA: Massachusetts Medical Society

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