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Seroprevalence of SARS-CoV-2 Binding and Neutralizing Antibodies in Healthcare Workers during the Epidemic Peak in Referral Hospitals and Quarantine Sites: Saudi Arabia

Alhabbab, Rowa Y. ; Alsaieedi, Ahdab ; Algaissi, Abdullah ; Almahboub, Sara ; Al-Raddadi, Rajaa M. ; Shabouni, Omaima I. ; Alhabbab, Rahaf ; Alfaraj, Abdulelah A. ; Alamri, Sawsan S. ; Aljehani, Najwa D. ; Abdulal, Rwaa H. ; Alfaleh, Mohamed A. ; Abujamel, Turki S. ; Alkayyal, Almohanad A. ; Mahmoud, Ahmad Bakur ; Abuzenadah, Adel M. ; Hashem, Anwar M.

Viruses, 2021-07, Vol.13 (7), p.1413 [Periódico revisado por pares]

Basel: MDPI AG

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Título:
Seroprevalence of SARS-CoV-2 Binding and Neutralizing Antibodies in Healthcare Workers during the Epidemic Peak in Referral Hospitals and Quarantine Sites: Saudi Arabia
Autor: Alhabbab, Rowa Y. ; Alsaieedi, Ahdab ; Algaissi, Abdullah ; Almahboub, Sara ; Al-Raddadi, Rajaa M. ; Shabouni, Omaima I. ; Alhabbab, Rahaf ; Alfaraj, Abdulelah A. ; Alamri, Sawsan S. ; Aljehani, Najwa D. ; Abdulal, Rwaa H. ; Alfaleh, Mohamed A. ; Abujamel, Turki S. ; Alkayyal, Almohanad A. ; Mahmoud, Ahmad Bakur ; Abuzenadah, Adel M. ; Hashem, Anwar M.
Assuntos: anti-S Abs ; Antibodies ; Asymptomatic ; Coronaviruses ; COVID-19 ; COVID-19 pandemic ; Disease transmission ; Epidemics ; HCWs ; Hospitals ; Infections ; Jeddah ; Medical personnel ; Middle East respiratory syndrome ; Pandemics ; Proteins ; Quarantine ; SARS-CoV-2 ; Serology ; seroprevalence ; Severe acute respiratory syndrome coronavirus 2
É parte de: Viruses, 2021-07, Vol.13 (7), p.1413
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Descrição: Healthcare workers (HCWs) are at high risk for SARS-CoV-2 infection compared to the general population. Here, we aimed to evaluate and characterize the SARS-CoV-2 seropositivity rate in randomly collected samples among HCWs from the largest referral hospitals and quarantine sites during the peak of the COVID-19 epidemic in the city of Jeddah, the second largest city in Saudi Arabia, using a cross-sectional analytic study design. Out of 693 participants recruited from 29 June to 10 August 2020, 223 (32.2%, 95% CI: 28.8–35.8) were found to be confirmed seropositive for SARS-CoV-2 antibodies, and among those 197 (88.3%) had never been diagnosed with COVID-19. Seropositivity was not significantly associated with participants reporting COVID-19 compatible symptoms as most seropositive HCW participants 140 (62.8%) were asymptomatic. The large proportion of asymptomatic SARS-CoV-2 cases detected in our study demands periodic testing as a general hospital policy.
Editor: Basel: MDPI AG
Idioma: Inglês

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Seroprevalence of SARS-CoV-2 Binding and Neutralizing Antibodies in Healthcare Workers during the Epidemic Peak in Referral Hospitals and Quarantine Sites: Saudi Arabia

Basel: MDPI AG

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