skip to main content
Idioma:
Primo Search
Clear Search Box
Search in: Busca Geral
Busca Avançada
Busca por Índices
Tipo de recurso Mostra resultados com: Mostra resultados com: Índice

Cardiac sarcoidosis with severe involvement of the right ventricle: a case report

Siqueira, Weverton César; Cruz, Samuel Gonçalves Da; Asimaki, Angeliki; Saffitz, Jeffrey Ern; Moreira, Maria Da Consolação Vieira; Brasileiro Filho, Geraldo; Rocha, Luiz Otávio Savassi

Autopsy and Case Reports; Vol. 5 Núm. 4 (2015); 53-63

Universidade de São Paulo. Hospital Universitário 2015-12-10

Acesso online

  • Título:
    Cardiac sarcoidosis with severe involvement of the right ventricle: a case report
  • Autor: Siqueira, Weverton César; Cruz, Samuel Gonçalves Da; Asimaki, Angeliki; Saffitz, Jeffrey Ern; Moreira, Maria Da Consolação Vieira; Brasileiro Filho, Geraldo; Rocha, Luiz Otávio Savassi
  • Assuntos: Sarcoidosis; Arrhythmogenic Right Ventricular Cardiomyopathy; Immunohistochemistry; Heart Diseases
  • É parte de: Autopsy and Case Reports; Vol. 5 Núm. 4 (2015); 53-63
  • Descrição: We present the case of a patient who underwent cardiac transplantation with the diagnosis of idiopathic dilated cardiomyopathy. Once the explanted heart was examined, a type of granulomatous myocarditis compatible with cardiac sarcoidosis was observed. However, there was severe involvement of the right ventricle, with markedly reduced width of the muscular layer and extensive fibrofatty replacement, findings similar to the ones encountered in cases of arrhythmogenic right ventricular cardiomyopathy (ARVC). Confocal immunofluorescence analysis revealed a reduced signal for plakoglobin and desmoplakin at the cardiac intercalated disks. The immunoreactive signal for desmin showed the typical sarcomeric distribution but not a concentrated signal at the intercalated disks, a pattern previously seen in an 11-year-old girl with Carvajal syndrome bearing a C-terminal truncating mutation in the desmoplakin gene. This case illustrates the difficult and challenging work involved in performing a differential diagnosis among idiopathic dilated cardiomyopathy, isolated cardiac sarcoidosis, and ARVC, all of which are clinical entities known to masquerade as one another
  • Títulos relacionados: https://www.revistas.usp.br/autopsy/article/view/116313/113925
  • Editor: Universidade de São Paulo. Hospital Universitário
  • Data de criação/publicação: 2015-12-10
  • Formato: Adobe PDF
  • Idioma: Inglês
Links
Voltar para lista de resultados

  • Realização: ABCD-USP USP   Logos de Redes Sociais: Freepik

Buscando em bases de dados remotas. Favor aguardar.