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Predictors of Mortality and Cardiovascular Outcome at 6 Months after Hospitalization for COVID-19

Renda, Giulia ; Ricci, Fabrizio ; Spinoni, Enrico Guido ; Grisafi, Leonardo ; D'Ardes, Damiano ; Mennuni, Marco ; Tana, Claudio ; Rognoni, Andrea ; Bellan, Mattia ; Sainaghi, Pier Paolo ; Pirisi, Mario ; De Vecchi, Simona ; Gallina, Sabina ; Pierdomenico, Sante Donato ; Cipollone, Francesco ; Patti, Giuseppe

Journal of clinical medicine, 2022-01, Vol.11 (3), p.729 [Periódico revisado por pares]

Switzerland: MDPI AG

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Título:
Predictors of Mortality and Cardiovascular Outcome at 6 Months after Hospitalization for COVID-19
Autor: Renda, Giulia ; Ricci, Fabrizio ; Spinoni, Enrico Guido ; Grisafi, Leonardo ; D'Ardes, Damiano ; Mennuni, Marco ; Tana, Claudio ; Rognoni, Andrea ; Bellan, Mattia ; Sainaghi, Pier Paolo ; Pirisi, Mario ; De Vecchi, Simona ; Gallina, Sabina ; Pierdomenico, Sante Donato ; Cipollone, Francesco ; Patti, Giuseppe
Assuntos: Age ; Anticoagulants ; Beta blockers ; Cardiac and Cardiovascular Systems ; Cardiac arrhythmia ; Cardiovascular events ; Clinical Medicine ; Coronaviruses ; COVID-19 ; Diuretics ; Dyspnea ; Follow-up ; Heart failure ; Hospitalization ; Hospitals ; Infections ; Kardiologi ; Kidney diseases ; Klinisk medicin ; Length of stay ; Medical and Health Sciences ; Medical prognosis ; Medicin och hälsovetenskap ; Mortality ; Neutrophils ; Pandemics ; Severe acute respiratory syndrome coronavirus 2 ; Software ; Vein & artery diseases
É parte de: Journal of clinical medicine, 2022-01, Vol.11 (3), p.729
Notas: ObjectType-Article-1
SourceType-Scholarly Journals-1
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These authors contributed equally to this work.
Descrição: Clinical outcome data of patients discharged after Coronavirus disease 2019 (COVID-19) are limited and no study has evaluated predictors of cardiovascular prognosis in this setting. Our aim was to assess short-term mortality and cardiovascular outcome after hospitalization for COVID-19. A prospective cohort of 296 consecutive patients discharged after COVID-19 from two Italian institutions during the first wave of the pandemic and followed up to 6 months was included. The primary endpoint was all-cause mortality. The co-primary endpoint was the incidence of the composite outcome of major adverse cardiac and cerebrovascular events (MACCE: cardiovascular death, myocardial infarction, stroke, pulmonary embolism, acute heart failure, or hospitalization for cardiovascular causes). The mean follow-up duration was 6 ± 2 months. The incidence of all-cause death was 4.7%. At multivariate analysis, age was the only independent predictor of mortality (aHR 1.08, 95% CI 1.01-1.16). MACCE occurred in 7.2% of patients. After adjustment, female sex (aHR 2.6, 95% CI 1.05-6.52), in-hospital acute heart failure during index hospitalization (aHR 3.45, 95% CI 1.19-10), and prevalent atrial fibrillation (aHR 3.05, 95% CI 1.13-8.24) significantly predicted the incident risk of MACCE. These findings may help to identify patients for whom a closer and more accurate surveillance after discharge for COVID-19 should be considered.
Editor: Switzerland: MDPI AG
Idioma: Inglês

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Predictors of Mortality and Cardiovascular Outcome at 6 Months after Hospitalization for COVID-19

Switzerland: MDPI AG

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