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Drug design for neuroscience

Alan P Kozikowski

New York Raven Press c1993

Localização: FCFRP - Fac. Ciên. Farm. Ribeirão Preto    (615.214.31 K88d )(Acessar)

  • Título:
    Drug design for neuroscience
  • Autor: Alan P Kozikowski
  • Assuntos: Psychotropic drugs -- Design; Brain Diseases -- drug therapy; Drug Design; Receptors, Cell Surface -- antagonists & inhibitors; Receptors, Cell Surface -- drug effects; FÁRMACOS
  • Notas: Includes bibliographical references and index
  • Descrição: Neurotransmitter receptors as pharmacological targets in Alzheimer's disease: design of drugs on a rational basis / Povl Krogsgaard-Larsen -- Design and synthesis of BMY 21502: a potential memory and cognition enhancing agent / Ronald J. Mattsonand Joseph P. Yevich -- Muscarinic agonists for the central nervous system / Raymond Baker and Angus M. MacLeod -- Novel organic reactions in the search for anxioselective anxiolytics at the benzodiazepine rec eptor / Weijiang Zhang and James M.Cook -- Design of orally active dopamine autoreceptor agonists / Lawrence D. Wise and Juan C. Jaen -- 3gbs-(substituted phenyl)tropan-2-carboxylic acid ester analogues of cocaine: synthesis and biochemical and pharmacological properties / F.Ivy Carroll ... [et al.] -- Serotonin receptors, agents, and actions / Jeffrey L. Herndon and Richard A. Glennon -- Studies of a novel series of thiazole-containing 5-hydroxytr yptamine-3 receptor antagonists / Terry Rosen, Arthur A. Nagel andJames P. Rizzi
    (cont) Conformationally constrained acidic amino acids as probes of glutamate receptors and transporters / Richard Chamberlin and Richard Bridges -- L-2-(carboxycyclopropyl)glycines: conformationally constrained L-glutamate ana logues / YasufumiOhfune and Haruhiko Shinozaki -- Design and synthesis of conformationally constrained acidic amino acids as N-methyl-D-aspartic acid receptor antagonists / Paul L. Ornstein -- Modulation of the N-methyl-D-aspar tate (NMDA) receptor complex:design and synthesis of competitive NMDA antagonists and phencyclidine (PCP)-site ligands / Christopher F. Bigge ... [et al.] -- Glycine-site N-methyl-D-aspartate receptor antagonists / Paul D. Lees on -- Synthetic inositol polyphosphates andanalogues as molecular probes for neuronal second messenger receptors / Barry V.L. Potter and Stefan R. Nahorski -- Inositol 1,4,5-triphosphate affinity chromatography: fishing out nov el ins(1,4,5)Pb3s-recognizable proteins / Shoichiro Ozaki... [et al.] -- Chemical approaches to brain-targ
  • Editor: New York Raven Press
  • Data de criação/publicação: c1993
  • Formato: xiii, 480 p. ill. (some col.) 24 cm.
  • Idioma: Inglês

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