skip to main content
Idioma:
Primo Search
Clear Search Box
Search in: Busca Geral
Busca Avançada
Busca por Índices

Enantioselective C−H Activation with Earth‐Abundant 3d Transition Metals

Loup, Joachim ; Dhawa, Uttam ; Pesciaioli, Fabio ; Wencel‐Delord, Joanna ; Ackermann, Lutz

Angewandte Chemie (International ed.), 2019-09, Vol.58 (37), p.12803-12818 [Periódico revisado por pares]

Germany: Wiley Subscription Services, Inc

Texto completo disponível

Citações Citado por
  • Título:
    Enantioselective C−H Activation with Earth‐Abundant 3d Transition Metals
  • Autor: Loup, Joachim ; Dhawa, Uttam ; Pesciaioli, Fabio ; Wencel‐Delord, Joanna ; Ackermann, Lutz
  • Assuntos: 3d metals ; Activation ; asymmetric catalysis ; Catalysis ; Catalysts ; Chemical Sciences ; chiral ligands ; C−H activation ; Enantiomers ; Heavy metals ; Iridium ; Metals ; Organic chemistry ; Palladium ; Pharmaceutical industry ; Plant protection ; Rhodium ; Substrates ; Transition metals
  • É parte de: Angewandte Chemie (International ed.), 2019-09, Vol.58 (37), p.12803-12818
  • Notas: Dedicated to Professor Armin de Meijere on the occasion of his 80th birthday
    These authors contributed equally to this work.
  • Descrição: Molecular syntheses largely rely on time‐ and labour‐intensive prefunctionalization strategies. In contrast, C−H activation represents an increasingly powerful approach that avoids lengthy syntheses of prefunctionalized substrates, with great potential for drug discovery, the pharmaceutical industry, material sciences, and crop protection, among others. The enantioselective functionalization of omnipresent C−H bonds has emerged as a transformative tool for the step‐ and atom‐economical generation of chiral molecular complexity. However, this rapidly growing research area remains dominated by noble transition metals, prominently featuring toxic palladium, iridium and rhodium catalysts. Indeed, despite significant achievements, the use of inexpensive and sustainable 3d metals in asymmetric C−H activations is still clearly in its infancy. Herein, we discuss the remarkable recent progress in enantioselective transformations via organometallic C−H activation by 3d base metals up to April 2019. Abundant and inexpensive: Inexpensive naturally occurring 3d transition metals with low toxicitiy faciliate enantioselective C−H activation thanks to novel ligand design.
  • Editor: Germany: Wiley Subscription Services, Inc
  • Idioma: Inglês
Links
Voltar para lista de resultados

  • Realização: ABCD-USP USP   Logos de Redes Sociais: Freepik

Buscando em bases de dados remotas. Favor aguardar.