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Contribution of the Portuguese Laboratory Network for the Diagnosis of Influenza A(H1N1)pdm09 infection during the 2009/10 and 2010/11 influenza seasons

Portuguese Laboratory Network for t, Collective

Euro surveillance : bulletin européen sur les maladies transmissibles, 2012-07, Vol.17 (27), p.1 [Periódico revisado por pares]

Sweden: Centre Europeen pour la Surveillance Epidemiologique du SIDA (European Centre for the Epidemiological Monitoring of AIDS)

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Título:
Contribution of the Portuguese Laboratory Network for the Diagnosis of Influenza A(H1N1)pdm09 infection during the 2009/10 and 2010/11 influenza seasons
Autor: Portuguese Laboratory Network for t, Collective
Assuntos: Acute Disease ; Adolescent ; Adult ; Age Distribution ; Aged ; Base Sequence ; Child ; Child, Preschool ; Female ; Genetics ; Hemagglutination Inhibition Tests ; Humans ; Infant ; Infant, Newborn ; Influenza ; Influenza A Virus, H1N1 Subtype - genetics ; Influenza A Virus, H1N1 Subtype - immunology ; Influenza A Virus, H1N1 Subtype - isolation & purification ; Influenza Vaccines - immunology ; Influenza, Human - diagnosis ; Influenza, Human - epidemiology ; Influenza, Human - prevention & control ; Influenza, Human - virology ; Laboratories ; Male ; Medical diagnosis ; Middle Aged ; Neuraminidase - genetics ; Pandemics ; Population Surveillance ; Portugal - epidemiology ; Real-Time Polymerase Chain Reaction ; Respiratory diseases ; Respiratory Tract Infections - epidemiology ; Respiratory Tract Infections - etiology ; Seasons ; Sex Distribution ; Virology ; Young Adult
É parte de: Euro surveillance : bulletin européen sur les maladies transmissibles, 2012-07, Vol.17 (27), p.1
Notas: ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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Descrição: This article describes the data obtained by the Portuguese Laboratory Network, reactivated following the World Health Organization declaration of the 2009 influenza pandemic, on the diagnoses of influenza A(H1N1)pdm09 infection during the pandemic (2009/10) and post-pandemic (2010/11) influenza seasons. The laboratories analysed and reported cases of influenza-like illness (ILI) and severe acute respiratory infection (SARI) to the National Influenza Reference Laboratory, which performed more detailed antigenic and genetic characterisation of the virus isolates. In 2009/10, a total of 62,089 ILI cases, distributed in two peaks, were analysed, 25,985 of which were positive for influenza A(H1N1)pdm09. Children aged 5–14 years were the most affected. Viruses were both antigenically and genetically similar to the pandemic strain A/California/7/2009, included in the 2009/10 pandemic vaccine. During the post-pandemic season, 1,496 ILI cases were tested for influenza A(H1N1) pdm09, 572 of which were positive. Infection was mainly diagnosed in adolescent and adults. Although the 2010/11 viruses remained antigenically similar to A/California/7/2009, increased genetic variation was observed. During the two seasons, two viruses with the neuraminidase H275Y amino acid substitution, associated with oseltamivir resistance, were detected. The Laboratory Network made an important contribution to the description of the influenza activity in the two seasons.
Editor: Sweden: Centre Europeen pour la Surveillance Epidemiologique du SIDA (European Centre for the Epidemiological Monitoring of AIDS)
Idioma: Inglês

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Contribution of the Portuguese Laboratory Network for the Diagnosis of Influenza A(H1N1)pdm09 infection during the 2009/10 and 2010/11 influenza seasons

Portuguese Laboratory Network for t, Collective

Sweden: Centre Europeen pour la Surveillance Epidemiologique du SIDA (European Centre for the Epidemiological Monitoring of AIDS)

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