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30-Day Post-Discharge Prophylaxis with Rivaroxaban Prevents Porto-mesenteric Venous Thrombosis Following Laparoscopic Sleeve Gastrectomy

Swartz, Daniel E. ; Hood, Lisa ; Swartz, Devin R. ; Gupta, Sachin

Obesity surgery, 2023-04, Vol.33 (4), p.1026-1031 [Periódico revisado por pares]

New York: Springer US

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Título:
30-Day Post-Discharge Prophylaxis with Rivaroxaban Prevents Porto-mesenteric Venous Thrombosis Following Laparoscopic Sleeve Gastrectomy
Autor: Swartz, Daniel E. ; Hood, Lisa ; Swartz, Devin R. ; Gupta, Sachin
Assuntos: Aftercare ; Anticoagulants - therapeutic use ; Gastrectomy - adverse effects ; Gastrectomy - methods ; Humans ; Laparoscopy - adverse effects ; Laparoscopy - methods ; Medicine ; Medicine & Public Health ; Mesenteric Ischemia - etiology ; Mesenteric Ischemia - prevention & control ; Mesenteric Ischemia - surgery ; Obesity, Morbid - surgery ; Original Contributions ; Patient Discharge ; Portal Vein ; Postoperative Complications - etiology ; Retrospective Studies ; Rivaroxaban - therapeutic use ; Surgery ; Venous Thrombosis - etiology ; Venous Thrombosis - prevention & control
É parte de: Obesity surgery, 2023-04, Vol.33 (4), p.1026-1031
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SourceType-Scholarly Journals-1
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Descrição: Introduction Porto-mesenteric venous thrombosis (PMVT) is a significant complication that occurs more frequently after laparoscopic sleeve gastrectomy (SG) than other bariatric procedures and presents later than other venous thromboembolic (VTE) events often 2 weeks after the operation. The common current practice in bariatric surgery of perioperative chemoprophylaxis until discharge may not adequately prevent PMVT. Therefore, a 30-day post-discharge chemoprophylaxis (PDC) might reduce the incidence of PMVT. The objective of this study is to determine whether 30-day PDC with rivaroxaban 10 mg daily following SG can reduce the incidence of PMVT. Methods In a retrospective cohort study, 292 consecutive patients undergoing SG by a single surgeon were either prescribed rivaroxaban 10 mg daily for 30 days upon discharge (group A) or did not receive any PDC (group B). Primary outcome was PMVT and secondary outcome was bleeding. Patients on chronic anticoagulation therapy were excluded from the study. Results PMVT events differences were significant between the groups while bleeding events were not. Group A had zero PMVT events, while group B had four ( p = .045). There were 4 bleeding events in group A and 7 bleeding events on group B ( p = .341). Conclusion A 30-day PDC regimen of rivaroxaban 10 mg daily is both safe and effective. This study demonstrated zero PMVT events without an increased risk of bleeding using this regimen. Graphical Abstract
Editor: New York: Springer US
Idioma: Inglês

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30-Day Post-Discharge Prophylaxis with Rivaroxaban Prevents Porto-mesenteric Venous Thrombosis Following Laparoscopic Sleeve Gastrectomy

Swartz, Daniel E. ; Hood, Lisa ; Swartz, Devin R. ; Gupta, Sachin

New York: Springer US

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