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Recent advances in the use of vibrational chiroptical spectroscopic methods for stereochemical characterization of natural products

Batista Jr, João M ; Blanch, Ewan W ; Bolzani, Vanderlan da Silva

Natural product reports, 2015-01, Vol.32 (9), p.128-132 [Periódico revisado por pares]

England

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  • Título:
    Recent advances in the use of vibrational chiroptical spectroscopic methods for stereochemical characterization of natural products
  • Autor: Batista Jr, João M ; Blanch, Ewan W ; Bolzani, Vanderlan da Silva
  • Assuntos: Alkaloids ; Biological Products - chemistry ; Carbohydrates ; Circular Dichroism ; Coumarins ; Flavonoids ; Lignans ; Molecular Structure ; Peptides ; Terpenes
  • É parte de: Natural product reports, 2015-01, Vol.32 (9), p.128-132
  • Notas: Ewan Blanch was awarded his PhD in Physical Chemistry from the University of New England, Australia in 1996. After post docing at the University of Glasgow with Professor Laurence Barron he started a Lectureship at the University of Manchester, UK in 2003. In January 2015 he was appointed as a Professor of Physical Chemistry in the School of Applied Sciences at RMIT University in Australia. His research interests focus on using spectroscopic techniques to understand biomolecular structure, function and disease; and the application of these methods to natural products, disease mechanisms, pharmaceutical bioformulation, nanosensor development and food science.
    João M. Batista Jr. received a BS in Pharmacy-Biochemistry (2007) from São Paulo State University - UNESP, Brazil, and a PhD (2012) from the same university, supervised by Maysa Furlan. He was appointed Visiting Research Scholar (2009-10) at Syracuse University, USA, under the guidance of Laurence Nafie. After receiving his PhD, he continued at UNESP, where he carried out postdoctoral research with Vanderlan Bolzani. He worked as a Visiting Scientist at the University of Manchester (2012-13), under the direction of Ewan Blanch. He joined the Federal University of São Carlos - UFSCar in 2015, where he is a Young Investigator funded by FAPESP.
    Vanderlan S. Bolzani, PhD in Organic Chemistry, is full professor at São Paulo State University, Brazil. She is a Fellow of the RSC (UK), Member of the Brazilian Academy of Science, and has received several awards, most recently: 2014 CAPES-Elsevier Award; Distinguished Woman in Science Chemistry from ACS & IUPAC (2011); Simão Mathias Medal, the highest honor conferred by the Brazilian Chemical Society (2011). In 1993-1995, she had post-doctorate training at Virginia Polytechnic Institute with Prof. David Kingston, and in 2011 was visiting professor at Paris VI, UPMC. Currently she is a member of the L'Oreal-SAB and TWAS. Her research field is plant science, focused on isolation, bioactivity, metabolomics of secondary metabolites, and peptides from plants. She has published 203 articles, 1 book, 5 book chapters and has 4 patents issued. She is member of the Biota-FAPESP biodiversity program, since its creation in 2003.
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  • Descrição: Covering: 2000 to 2014 This review covers conformational and configurational assignments in natural product molecules using chiroptical spectroscopy reported over the last 15 years. Special attention is given to vibrational optical activity methods associated with quantum mechanical calculations. A comprehensive look into application of vibrational optical activity methods for conformational and configurational assignments in natural product molecules over the last 15 years is provided.
  • Editor: England
  • Idioma: Inglês

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