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A geometrically accurate 3 dimensional model of human thermoregulation for transient cold and hot environments

Castellani, Michael P. ; Rioux, Timothy P. ; Castellani, John W. ; Potter, Adam W. ; Xu, Xiaojiang

Computers in biology and medicine, 2021-11, Vol.138, p.104892-104892, Article 104892 [Periódico revisado por pares]

Oxford: Elsevier Ltd

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Título:
A geometrically accurate 3 dimensional model of human thermoregulation for transient cold and hot environments
Autor: Castellani, Michael P. ; Rioux, Timothy P. ; Castellani, John W. ; Potter, Adam W. ; Xu, Xiaojiang
Assuntos: Blood ; Body temperature ; Bones ; Cold ; Control of body temperature ; Finite element method ; Geometry ; Heat balance ; Heat conductivity ; Heat strain ; Heat transfer ; Human body ; Hypothalamus ; Intestine ; Metabolism ; Muscles ; Organs ; Physiology ; Regions ; Shivering ; Simulation ; Skin ; Software ; Spatial discrimination ; Spatial resolution ; Sweating ; Temperature ; Temperature distribution ; Thermal physiology ; Thermal simulation ; Thermoregulation ; Three dimensional models ; Tissues ; Vasoconstriction ; Vasodilation
É parte de: Computers in biology and medicine, 2021-11, Vol.138, p.104892-104892, Article 104892
Notas: ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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Descrição: This paper outlines the development of a finite element human thermoregulatory model using an anatomically and geometrically correct human body model. The finite element body model was constructed from digital Phantoms and is anatomically realistic, including 13 organs and tissues: skin, muscles, fat, bones, heart, lungs, brain, bladder, intestines, stomach, kidneys, liver, and eyes. The model simulates thermal responses through a passive and active system. The passive system describes heat balance within the body and between the skin surface and environment. The active system describes thermoregulatory mechanisms, i.e., vasodilation, vasoconstriction, sweating, and shivering heat production. This model predicts temperature distribution across the body at high spatial resolution, and provides insight into human thermoregulatory responses to non-uniform and transient environments. Predicted temperatures (i.e., core, skin, muscle and fat) at 29 sites were compared with measured values in comfort, hot, and cold conditions. The comprehensive validation shows predictions are accurate and acceptable. •Finite element model of human thermoregulation is developed•Body model is anatomically and geometrically realistic, includes 13 organs/tissues•The model predicts spatial temperature distribution across body at high resolution•Predicted core, skin, muscle and fat temperatures at 29 body sites are validated
Editor: Oxford: Elsevier Ltd
Idioma: Inglês

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A geometrically accurate 3 dimensional model of human thermoregulation for transient cold and hot environments

Castellani, Michael P. ; Rioux, Timothy P. ; Castellani, John W. ; Potter, Adam W. ; Xu, Xiaojiang

Oxford: Elsevier Ltd

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