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An overview of various mammalian models to study chronic copper intoxication associated Alzheimer’s disease like pathology

Pal, Amit ; Prasad, Rajendra

Biometals, 2015-02, Vol.28 (1), p.1-9 [Periódico revisado por pares]

Dordrecht: Springer Netherlands

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Título:
An overview of various mammalian models to study chronic copper intoxication associated Alzheimer’s disease like pathology
Autor: Pal, Amit ; Prasad, Rajendra
Assuntos: Alzheimer Disease - chemically induced ; Alzheimer Disease - pathology ; Alzheimer's disease ; Animals ; Biochemistry ; Biomedical and Life Sciences ; Cell Biology ; Central nervous system ; Central Nervous System - metabolism ; Central Nervous System - pathology ; Cognition - physiology ; Copper ; Copper - toxicity ; Disease Models, Animal ; Intoxication ; Life Sciences ; Liver ; Mammals ; Medicine/Public Health ; Microbiology ; Nervous system ; Neurodegeneration ; Neurodegenerative Diseases - chemically induced ; Neurodegenerative Diseases - pathology ; Pathology ; Pharmacology/Toxicology ; Plant Physiology ; Toxicity
É parte de: Biometals, 2015-02, Vol.28 (1), p.1-9
Notas: ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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Descrição: Chronic copper toxicity has been long known to cause hepatotoxicity and liver cirrhosis as observed in Wilson’s disease; however, substantial evidence accrued over the time have shown considerable increase in animal studies demonstrating Alzheimer’s disease like pathology due to chronic copper-intoxication under certain conditions. This review integrates the contemporary mammalian studies in which the effect of chronic copper intoxication was assessed on the central nervous system and cognition of animals.
Editor: Dordrecht: Springer Netherlands
Idioma: Inglês;Holandês

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An overview of various mammalian models to study chronic copper intoxication associated Alzheimer’s disease like pathology

Pal, Amit ; Prasad, Rajendra

Dordrecht: Springer Netherlands

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