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DIAGNOSIS OF ENDOCRINE DISEASE: Expanding the cause of hypopituitarism

Pekic, Sandra ; Popovic, Vera

European journal of endocrinology, 2017-06, Vol.176 (6), p.R269-R282 [Periódico revisado por pares]

England: Bioscientifica Ltd

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Título:
DIAGNOSIS OF ENDOCRINE DISEASE: Expanding the cause of hypopituitarism
Autor: Pekic, Sandra ; Popovic, Vera
Assuntos: Adenoma ; Adenoma - complications ; Adenoma - diagnosis ; Brain Abscess - complications ; Brain Abscess - diagnosis ; Brain Injuries, Traumatic - complications ; Central Nervous System Infections - complications ; Central Nervous System Infections - diagnosis ; Cranial Irradiation - adverse effects ; Diagnosis ; Diagnosis, Differential ; Early Diagnosis ; Early Medical Intervention ; Erdheim-Chester Disease - complications ; Erdheim-Chester Disease - diagnosis ; Genetic disorders ; Glomus Tumor - complications ; Glomus Tumor - diagnosis ; Granulomatosis with Polyangiitis - complications ; Granulomatosis with Polyangiitis - diagnosis ; Hemochromatosis ; Hemochromatosis - complications ; Hemochromatosis - diagnosis ; Hemosiderosis - complications ; Hemosiderosis - diagnosis ; Histiocytosis, Langerhans-Cell - complications ; Histiocytosis, Langerhans-Cell - diagnosis ; Hormone Replacement Therapy ; Humans ; Hypophysitis - complications ; Hypophysitis - diagnosis ; Hypopituitarism ; Hypopituitarism - diagnosis ; Hypopituitarism - drug therapy ; Hypopituitarism - etiology ; Hypothalamus ; Infectious diseases ; Inflammatory diseases ; Intracranial Aneurysm - complications ; Intracranial Aneurysm - diagnosis ; Life span ; Lymphoma - complications ; Lymphoma - diagnosis ; Neurosyphilis - complications ; Neurosyphilis - diagnosis ; Pituitary ; Pituitary Apoplexy - complications ; Pituitary Apoplexy - diagnosis ; Pituitary hormones ; Pituitary Neoplasms - complications ; Pituitary Neoplasms - diagnosis ; Pituitary Neoplasms - secondary ; Plasmacytoma - complications ; Plasmacytoma - diagnosis ; Puerperal Disorders - diagnosis ; Quality of life ; Review ; Sarcoidosis ; Sarcoidosis - complications ; Sarcoidosis - diagnosis ; Sella Turcica ; Subarachnoid Hemorrhage - complications ; Subarachnoid Hemorrhage - diagnosis ; Traumatic brain injury ; Tuberculosis, Central Nervous System - complications ; Tuberculosis, Central Nervous System - diagnosis
É parte de: European journal of endocrinology, 2017-06, Vol.176 (6), p.R269-R282
Descrição: Hypopituitarism is defined as one or more pituitary hormone deficits due to a lesion in the hypothalamic–pituitary region. By far, the most common cause of hypopituitarism associated with a sellar mass is a pituitary adenoma. A high index of suspicion is required for diagnosing hypopituitarism in several other conditions such as other massess in the sellar and parasellar region, brain damage caused by radiation and by traumatic brain injury, vascular lesions, infiltrative/immunological/inflammatory diseases (lymphocytic hypophysitis, sarcoidosis and hemochromatosis), infectious diseases and genetic disorders. Hypopituitarism may be permanent and progressive with sequential pattern of hormone deficiencies (radiation-induced hypopituitarism) or transient after traumatic brain injury with possible recovery occurring years from the initial event. In recent years, there is increased reporting of less common and less reported causes of hypopituitarism with its delayed diagnosis. The aim of this review is to summarize the published data and to allow earlier identification of populations at risk of hypopituitarism as optimal hormonal replacement may significantly improve their quality of life and life expectancy.
Editor: England: Bioscientifica Ltd
Idioma: Inglês

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DIAGNOSIS OF ENDOCRINE DISEASE: Expanding the cause of hypopituitarism

Pekic, Sandra ; Popovic, Vera

England: Bioscientifica Ltd

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