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Breast-specific gamma imaging in breast cancer

van Loevezijn, Ariane A ; van Breda Vriesman, Adriaan C ; Neijenhuis, Peter A ; Pereira Arias-Bouda, Lenka M

Nederlands tijdschrift voor geneeskunde, 2016, Vol.160, p.A9610

Netherlands

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Título:
Breast-specific gamma imaging in breast cancer
Autor: van Loevezijn, Ariane A ; van Breda Vriesman, Adriaan C ; Neijenhuis, Peter A ; Pereira Arias-Bouda, Lenka M
Assuntos: Breast - diagnostic imaging ; Breast - pathology ; Breast Neoplasms - diagnosis ; Breast Neoplasms - diagnostic imaging ; Breast Neoplasms - pathology ; Female ; Gamma Cameras - standards ; Humans ; Magnetic Resonance Imaging - methods ; Mammography ; Organ Specificity ; Radionuclide Imaging ; Sensitivity and Specificity ; Technetium Tc 99m Sestamibi
É parte de: Nederlands tijdschrift voor geneeskunde, 2016, Vol.160, p.A9610
Descrição: Breast-specific gamma imaging (BSGI) is a new technique in nuclear medicine for the diagnosis of breast cancer. After intravenous injection of the radioactive substance 99mTc-sestamibi the breasts are imaged with a gamma camera. The radionuclide assimilates into intracellular mitochondria, which are present in greater numbers in breast cancer cells than in normal cells. This causes a relatively high uptake of the radionuclide in tumours. Along with mammography and ultrasound, MRI is the current gold standard in breast imaging diagnostics. However, MRI is a complex and expensive procedure and has low specificity leading to high false-positive rates. BSGI has equally high sensitivity but is more specific, cheaper and much simpler to interpret. BSGI could replace MRI as a complementary technique to show, exclude or indicate the extent of breast cancer.
Editor: Netherlands
Idioma: Holandês

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Breast-specific gamma imaging in breast cancer

van Loevezijn, Ariane A ; van Breda Vriesman, Adriaan C ; Neijenhuis, Peter A ; Pereira Arias-Bouda, Lenka M

Netherlands

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