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Liquid-liquid extraction by reversed micelles in biotechnological processes

Kilikian, B. V. ; Bastazin, M. R. ; Minami, N. M. ; Gonçalves, E. M. R. ; Junior, A. P.

Brazilian journal of chemical engineering, 2000-03, Vol.17 (1), p.29-38 [Periódico revisado por pares]

Brazilian Society of Chemical Engineering

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  • Título:
    Liquid-liquid extraction by reversed micelles in biotechnological processes
  • Autor: Kilikian, B. V. ; Bastazin, M. R. ; Minami, N. M. ; Gonçalves, E. M. R. ; Junior, A. P.
  • Assuntos: Biotechnology ; Cell culture ; ENGINEERING, CHEMICAL ; Enzymes ; Fermentation ; Micelles ; Nucleic acids ; Organic solvents ; Purification ; Surface active agents
  • É parte de: Brazilian journal of chemical engineering, 2000-03, Vol.17 (1), p.29-38
  • Notas: ObjectType-Article-2
    SourceType-Scholarly Journals-1
    ObjectType-Feature-1
    content type line 23
  • Descrição: In biotechnology there is a need for new purification and concentration processes for biologically active compounds such as proteins, enzymes, nucleic acids, or cells that combine a high selectivity and biocompatibility with an easy scale-up. A liquid-liquid extraction with a reversed micellar phase might serve these purposes owing to its capacity to solubilize specific biomolecules from dilute aqueous solutions such as fermentation and cell culture media. Reversed micelles are aggregates of surfactant molecules containing an inner core of water molecules, dispersed in a continuous organic solvent medium. These reversed micelles are capable of selectively solubilizing polar compounds in an apolar solvent. This review gives an overview of liquid-liquid extraction by reversed micelles for a better understanding of this process.
  • Editor: Brazilian Society of Chemical Engineering
  • Idioma: Inglês;Português

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