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In Search of Lost Biomarker for Immunotherapy in Small Cell Lung Cancer

Rolfo, Christian ; Russo, Alessandro

Clinical cancer research, 2024-02, Vol.30 (4), p.652-OF3 [Periódico revisado por pares]

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Título:
In Search of Lost Biomarker for Immunotherapy in Small Cell Lung Cancer
Autor: Rolfo, Christian ; Russo, Alessandro
Assuntos: Antineoplastic Combined Chemotherapy Protocols - therapeutic use ; Biomarkers, Tumor - therapeutic use ; Etoposide - therapeutic use ; Humans ; Immunotherapy ; Lung Neoplasms - drug therapy ; Lung Neoplasms - genetics ; Small Cell Lung Carcinoma - drug therapy ; Small Cell Lung Carcinoma - genetics
É parte de: Clinical cancer research, 2024-02, Vol.30 (4), p.652-OF3
Notas: ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
ObjectType-Commentary-3
content type line 23
Descrição: Chemo-immunotherapy is the current standard of care for extensive-stage small cell lung cancer, but predictive biomarkers are lacking. In a recent article, the authors report the predictive role of programmed death ligand-1 expression and tissue tumor mutational burden on durvalumab ± tremelimumab + platinum-etoposide efficacy. See related article by Paz-Ares et al., p. 824.
Editor: United States
Idioma: Inglês

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