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Waiting for the Revolution

MARSHALL, ELIOT

Science (American Association for the Advancement of Science), 2011-02, Vol.331 (6017), p.526-529 [Periódico revisado por pares]

American Association for the Advancement of Science

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  • Título:
    Waiting for the Revolution
  • Autor: MARSHALL, ELIOT
  • Assuntos: Cancer ; DNA ; Genetic mutation ; Genomics ; Human genetics ; Human genome ; HUMAN GENOME 10TH ANNIVERSARY ; Lynch syndrome II ; Medical genetics ; Primary health care ; Tumors
  • É parte de: Science (American Association for the Advancement of Science), 2011-02, Vol.331 (6017), p.526-529
  • Descrição: Having the complete human DNA sequence hasn't yet produced big advances in primary medicine, prompting some to ask what's delaying the genomic revolution in health care. Medical schools and research centers are investing tens of millions of dollars each to join the genomic medicine bandwagon. Yet some say this is a huge leap into uncharted clinical territory. Most doctors have not embraced the genomic revolution, according to leaders of medical professional groups, because they have trouble seeing how it will benefit their patients. DNA testing is growing rapidly in oncology to guide the treatment of some cancers and in screening couples before conception and newborns to find dangerous mutations, and many labs are developing therapies to narrowly target tumor DNA. But aside from these situations, applications are scant; most public health reviews of DNA-based approaches have not found a health benefit. As doctors and scientists look back over the decade since the human genome was published, some are asking tough questions. Is the translation of DNA research into medical practice taking longer than expected? Has the genomic medicine revolution faltered? This News story and another on gene patents (p. 530 ) launch a series of features this month commemorating the 10th anniversary of Science 's and Nature 's publications of the human genome, which are gathered here .
  • Editor: American Association for the Advancement of Science
  • Idioma: Inglês
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  • Realização: ABCD-USP USP   Logos de Redes Sociais: Freepik

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