Idioma:

Methicillin‐resistant and vancomycin‐intermediate Staphylococcus aureus colonizing patients and intensive care unit environment: virulence profile and genetic variability

Veloso, Jéssica O. ; Lamaro‐Cardoso, Juliana ; Neves, Lorrane S. ; Borges, Lizandra F. A. ; Pires, Cyndi H. ; Lamaro, Luana ; Guerreiro, Tainá C. ; Ferreira, Evelyn M. A. ; André, Maria Cláudia P.

APMIS : acta pathologica, microbiologica et immunologica Scandinavica, 2019-11, Vol.127 (11), p.717-726 [Periódico revisado por pares]

Denmark: Wiley Subscription Services, Inc

Texto completo disponível

Citações Citado por

Enviar para

Título:
Methicillin‐resistant and vancomycin‐intermediate Staphylococcus aureus colonizing patients and intensive care unit environment: virulence profile and genetic variability
Autor: Veloso, Jéssica O. ; Lamaro‐Cardoso, Juliana ; Neves, Lorrane S. ; Borges, Lizandra F. A. ; Pires, Cyndi H. ; Lamaro, Luana ; Guerreiro, Tainá C. ; Ferreira, Evelyn M. A. ; André, Maria Cláudia P.
Assuntos: Anti-Bacterial Agents - pharmacology ; Antiinfectives and antibacterials ; Bacterial Proteins - genetics ; Colonization ; Drug resistance ; Drug Resistance, Bacterial ; Environment ; Female ; Fomites ; Genetic relationship ; Genetic variability ; Genetic Variation ; Humans ; inanimate surfaces ; intensive care units ; Intensive Care Units - statistics & numerical data ; Male ; Methicillin ; Methicillin - pharmacology ; Methicillin Resistance ; Methicillin-Resistant Staphylococcus aureus - drug effects ; Methicillin-Resistant Staphylococcus aureus - genetics ; Methicillin-Resistant Staphylococcus aureus - growth & development ; Methicillin-Resistant Staphylococcus aureus - pathogenicity ; Methicillin‐resistant Staphylococcus aureus ; Microbial Sensitivity Tests ; Multidrug resistance ; Pathogens ; Penicillin ; Phylogeny ; Staphylococcal Infections - microbiology ; Staphylococcus aureus ; Staphylococcus aureus - drug effects ; Staphylococcus aureus - genetics ; Staphylococcus aureus - growth & development ; Staphylococcus aureus - pathogenicity ; Vancomycin ; Vancomycin - pharmacology ; vancomycin‐intermediate Staphylococcus aureus ; Virulence ; Virulence factors ; Virulence Factors - genetics
É parte de: APMIS : acta pathologica, microbiologica et immunologica Scandinavica, 2019-11, Vol.127 (11), p.717-726
Notas: ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
Descrição: This study aims to determine the prevalence of Staphylococcus aureus colonizing patients and ICU environment of a teaching hospital, the virulence and antimicrobial susceptibility profile of the isolates, and to evaluate the genetic relationship among them. A total of 536 swabs (134 of patients and 402 of ICU environment) were collected and analyzed to detect S. aureus. The antimicrobial susceptibility of the isolates was determined by disk diffusion test, and the detection of the mecA and virulence factors genes was performed by PCR, in addition to SCCmec typing. The genetic similarity of the isolates was determined by PFGE. Staphylococcus aureus was isolated in 12.7% of the swabs. The prevalence of colonization was 13.4% in patients and 12.4% in the environmental samples. The multidrug resistance was determined in 82.4% of the isolates. The prevalence of methicillin‐resistant S. aureus was 20.6%, with 50.0% classified as SCCmec IV. The intermediate resistance to vancomycin was detected in 5.9% and 4.4% of the isolates obtained from patients and environment, respectively. Identical isolates obtained from different patients and sources were grouped into several clusters. The results showed dissemination of multidrug‐resistant strains between patients and fomites and the persistence of MRSA and VISA isolates in the ICU environment.
Editor: Denmark: Wiley Subscription Services, Inc
Idioma: Inglês

Links

View this record in MEDLINE/PubMed

Voltar para lista de resultados

Realização: Logos de Redes Sociais:

Methicillin‐resistant and vancomycin‐intermediate Staphylococcus aureus colonizing patients and intensive care unit environment: virulence profile and genetic variability

Veloso, Jéssica O. ; Lamaro‐Cardoso, Juliana ; Neves, Lorrane S. ; Borges, Lizandra F. A. ; Pires, Cyndi H. ; Lamaro, Luana ; Guerreiro, Tainá C. ; Ferreira, Evelyn M. A. ; André, Maria Cláudia P.

Denmark: Wiley Subscription Services, Inc

Buscando em bases de dados remotas. Favor aguardar.