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In Vivo Release of Taurine from Rat Neostriatum and Substantia Nigra

Bianchi, Loria ; Bolam, John P. ; Galeffi, Francesca ; Frosini, Maria ; Palmi, Mitri ; Sgaragli, Gianpietro ; Corte, Laura Della

Advances in experimental medicine and biology, 1996, Vol.403, p.427-433 [Periódico revisado por pares]

Boston, MA: Springer US

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Título:
In Vivo Release of Taurine from Rat Neostriatum and Substantia Nigra
Autor: Bianchi, Loria ; Bolam, John P. ; Galeffi, Francesca ; Frosini, Maria ; Palmi, Mitri ; Sgaragli, Gianpietro ; Corte, Laura Della
Assuntos: Animals ; Cysteine Sulfinate ; Cysteine Sulfinate Decarboxylase ; Kainic Acid ; Kainic Acid - pharmacology ; Kinetics ; Male ; Models, Neurological ; Neostriatum - drug effects ; Neostriatum - metabolism ; Potassium - pharmacology ; Quinoxalines - pharmacology ; Rats ; Rats, Sprague-Dawley ; Substantia Nigra ; Substantia Nigra - drug effects ; Substantia Nigra - metabolism ; Taurine - metabolism ; Taurine Release ; Tetrodotoxin - pharmacology
É parte de: Advances in experimental medicine and biology, 1996, Vol.403, p.427-433
Descrição: Taurine has been shown to fulfil many of the criteria of a neurotransmitter in the basal ganglia. The neostriatum (STR) and substantia nigra (SN) contain high levels of taurine and its synthetic enzyme sulfinoalanine decarboxylase (EC 4.1.1.29, commonly referred to as cysteine sulfinic acid decarboxylase, CSDI)19, 29, 34, 41, 43, 45. The presence of a high affinity uptake system for taurine has been detected in both the STR11, 29 and SN14. Furthermore, uptake and release studies of exogenous radiolabelled taurine suggest that neurones identified as medium-size densely spiny striatonigral neurones contain taurine and release it at their terminals in the SN15 (see Table 1).
Editor: Boston, MA: Springer US
Idioma: Inglês

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In Vivo Release of Taurine from Rat Neostriatum and Substantia Nigra

Bianchi, Loria ; Bolam, John P. ; Galeffi, Francesca ; Frosini, Maria ; Palmi, Mitri ; Sgaragli, Gianpietro ; Corte, Laura Della

Boston, MA: Springer US

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