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Receptor-based drug design

Paul Leff

New York M. Dekker c1998

Localização: CQ - Conjunto das Químicas    (615.19 R295 ) e outros locais(Acessar)

  • Título:
    Receptor-based drug design
  • Autor: Paul Leff
  • Assuntos: Drug receptors; Drugs -- Design; G proteins; Ion channels; QUÍMICA FARMACÊUTICA; Drug Design; Receptors, Cell Surface -- physiology; Receptors, Cell Surface -- metabolism; G-Proteins -- physiology; Ligands
  • Notas: Includes bibliographical references and index
  • Descrição: pt. 1. Principles and measurement of drug-receptor interactions -- The characterization and classification of receptors -- Functional methods for quantifying agonists and antagonists -- Quantification of receptor interactions using bindingmethods -- Drug analysis based on signaling responses to G-protein-coupled receptors -- The use of electrophysiology to improve understanding of drug-receptor interactions -- pt. 2. Receptor-based drugs in medicine-- Selective adrenergic andglucocorticoid treatments for asthma -- Serotonin 5-HTb1sB/D receptor agonists -- Histamine Hb2s-receptor antagonists -- Angiotensin antagonists -- pt. 3. Experimental and emerging drugs -- gas-Adrenoceptor agonists and antagonists --Pb2sU-purinoceptor angonists: emerging therapy for pulmonary diseases -- Muscarinic receptor antagonists: pharmacological and therapeutic utility -- NMDA receptor antagonists -- pt. 4.New trends in drug design -- Computational chemistry inreceptor-based drug design -- Recombinant G-protein-coupled receptors as screening tools for drug discovery -- Inverse agonists and G-protein-coupled receptors
  • Títulos relacionados: Série:Drugs and the pharmaceutical sciences v. 89
  • Editor: New York M. Dekker
  • Data de criação/publicação: c1998
  • Formato: xi, 382 p. ill. 24 cm.
  • Idioma: Inglês
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  • Realização: ABCD-USP USP   Logos de Redes Sociais: Freepik

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